青岛大学学报（医学版）2023，Vol.59Issue(5)：730-734,5.DOI:10.11712/jms.2096-5532.2023.59.154
PRP并髋关节外科脱位打压植骨支撑术治疗早期股骨头坏死效果
EFFECT OF PLATELET-RICH PLASMA PLUS SURGICAL HIP DISLOCATION COMBINED WITH IMPACTING BONE GRAFTS IN THE TREATMENT OF EARLY-STAGE OSTEONECROSIS OF THE FEMORAL HEAD
摘要
Abstract
Objective To observe the short-term clinical efficacy and safety of platelet-rich plasma(PRP)plus surgical hip dislocation combined with impacting bone grafts in the treatment of early-stage osteonecrosis of the femoral head(ONFH).Methods A total of 60 patients with ONFH(60 hips)were selected and divided into observation group and control group accor-ding to the random number table method,with 30 patients in each group.Patients in the observation group received PRP injection plus surgical hip dislocation combined with impacting bone grafts,while those in the control group received surgical hip dislocation combined with impacting bone grafts.The postoperative follow-up period was 12-18 months(mean:(14.50±2.36)months).Harris hip scores,visual analogue scale(VAS)scores,postoperative drainage volume,and postoperative complications were com-pared between the two groups.Results All surgical incisions in the two groups healed by first intention without complications such as infection and venous thrombosis.At 12 months postoperatively,Harris hip score and VAS score were improved in both groups,and were significantly better in the observation group than in the control group(t=5.625,3.702;P＜0.05).Moreover,the drainage volume in the observation group was significantly less than that in the control group(t=-4.60,P＜0.05).Conclusion PRP plus surgical hip dislocation combined with impacting bone grafts has good short-term efficacy in the treatment of early-stage ONFH,without serious complications.This method is worthy of further clinical application.关键词
富血小板血浆/股骨头坏死/骨移植/治疗结果Key words
platelet-rich plasma/femur head necrosis/bone grafting/treatment outcome分类
医药卫生引用本文复制引用
赵春辉,韦标方..PRP并髋关节外科脱位打压植骨支撑术治疗早期股骨头坏死效果[J].青岛大学学报（医学版）,2023,59(5):730-734,5.基金项目
山东省优秀中青年科学家科研奖励基金计划项目(2014GSF119022) （2014GSF119022）
