日用化学品科学2023，Vol.46Issue(12)：31-37,7.DOI:10.3969/j.issn.1006-7264.2023.12.005
一种高糖群体身体护理霜的功效及机理研究
Study on the efficacy and mechanism of a body care cream for the people with hyperglycemia
摘要
Abstract
A kind of daily care product suitable for people with high blood sugar level was studied.A natural plant extract was obtained through formula screening,whose main effective components were apple extract and tea extract.A mouse model of high glucose was established and the product was applied on the skin for one cycle.The skin care effect was studied.The indexes of fasting blood glucose and blood lipid in the blank group and the experimental group were measured,as well as the expression of various cytokines in skin and blood and the pathological staining of the five organs of mice.Thus the influences of the cream in periodic use could be evaluated,including the aspects of blood glucose,antioxidant effect and biosafety.The results showed that the cream could improve the activities of catalase(CAT)and superoxide dismutase(SOD)in the skin of mice,and inhibit oxidative stress.The fasting blood glucose and blood indexes of mice were also monitored.The cream did not cause organ damage according to the observation of the five viscera sections.Therefore,this cream containing apple extract and tea extract as the main ingredients was suitable for the people with high blood sugar level,exhibiting antioxidation and good biosafety.关键词
苹果多酚/茶多酚/高糖群体/抗氧化Key words
apple polyphenol/tea polyphenol/high sugar/antioxidant分类
医药卫生引用本文复制引用
韦杏芳,张泽奇,袁燕燕,钱昱含,孙宇昂,杨平顺..一种高糖群体身体护理霜的功效及机理研究[J].日用化学品科学,2023,46(12):31-37,7.基金项目
南科大生医工系-容大生物康美联合实验室(K2138Z119) （K2138Z119）
