色谱2023，Vol.41Issue(12)：1052-1061,10.DOI:10.3724/SP.J.1123.2023.07003
微孔有机网络材料的合成方法及其在样品前处理中的应用进展
Advances in synthesis methods and applications of microporous organic networks for sample preparation
摘要
Abstract
Sample pretreatment is an essential step in chromatographic analysis.Solid phase extraction(SPE)is a widely used sample pretreatment method.In SPE,the quality of the ad-sorbent directly affects the adsorption and enrichment efficiency of the target compounds as well as the sensitivity and selectivity of the pretreatment and subsequent analysis.Therefore,the selection and development of adsorbents has become a research hotspot.Microporous or-ganic networks(MONs)are a novel type of covalent organic materials that are synthesized by the Sonogashira reaction of aromatic alkynes and aromatic halides.These networks have the ad-vantages of modifiable structures,large specific surface areas,high porosity,and simple syn-thesis methods.This paper reviews the synthesis and functional modification methods of MONs,with an emphasis on their applications in sample pretreatment.Future development trends are also prospected.In terms of synthesis,the preparation methods for MON-based ma-terials have progressed from reflux and solvothermal synthesis to room-temperature synthesis,the conditions of which tend to be milder and more efficient.In terms of functional modifica-tion,the introduction of macromolecules and active groups(including amino,hydroxyl,and carboxylic groups)can increase the selectivity and active sites of MON-based materials.The combination of MONs with Fe3 O4,SiO2,and metal organic frameworks yields core-shell-struc-tured MONs.Furtherly,they can be calcined and etched to form porous carbon structures or hollow multilayer materials.Functionalized MONs and their composite materials have multiple interaction mechanisms(e.g.,hydrogen bonding,hydrophobic,electrostatic,and π-π interac-tions)with various target compounds,thereby realizing their efficient extraction.MONs can be used as adsorbent materials in SPE,Solid phase microextraction,dispersed solid phase extrac-tion,magnetic solid phase extraction,and other pretreatment methods.When combined with chromatography and chromatography-mass spectrometry,MONs achieve good adsorption effects and high sensitivity,demonstrating the application potential of these materials in sample pretreatment.关键词
微孔有机网络/Sonogashira反应/样品前处理/固相萃取/吸附剂/综述Key words
microporous organic networks(MONs)/Sonogashira reaction/sample pretreat-ment/solid phase extraction/adsorbent/review分类
化学化工引用本文复制引用
余涛,陈立,张文敏,张兰,卢巧梅..微孔有机网络材料的合成方法及其在样品前处理中的应用进展[J].色谱,2023,41(12):1052-1061,10.基金项目
福建省自然科学基金(2021J01632,2021J01608,2023J05085). Natural Science Foundation of Fujian Province(Nos.2021J01632,2021J01608,2023J05085). （2021J01632,2021J01608,2023J05085）
