生物技术通报2023，Vol.39Issue(11)：150-167,18.DOI:10.13560/j.cnki.biotech.bull.1985.2023-0616
微生物硫代谢与抗逆性
Microbial Sulfur Metabolism and Stress Resistance
摘要
Abstract
Sulfur metabolism is an important life metabolism in microbes.Sulfur transportation,assimilation,metabolic regulation and biosynthesis of important sulfur-containing compounds by microorganisms not only affect the growth and metabolism of microorganisms,but also influence the stress resistance and robustness of microorganisms in inhibitory environments.Most of current researches are focusing on the microbial sulfate assimilatory reduction process and H2S production with few studies on microbial sulfur metabolism and stress resistance.This review summarized sulfate transport,assimilatory reduction pathway,and regulatory networks in the process of sulfur metabolism.Combined with the oxidative stress responses of microorganisms under different stress conditions,the review discussed mechanism by which sulfur-containing compounds such as hydrogen sulfide,glutathione and cysteine improve the stress resistance of microorganisms.The revelation of molecular mechanism between sulfur metabolism and microbial stress resistance will not only help understand microbial sulfur metabolism further,but also provide candidate molecular targets for the design and construction of efficient and robust industrial strains.关键词
硫代谢/氧化还原反应/胁迫耐受性/硫同化/H2SKey words
sulfur metabolism/oxidative stress responses/stress resistance/sulfate assimilation/H2S引用本文复制引用
晏雄鹰,王振,王霞,杨世辉..微生物硫代谢与抗逆性[J].生物技术通报,2023,39(11):150-167,18.基金项目
国家自然科学基金项目(22108064,21978071),国家重点研发计划项目(2022YFA0911800,2018YFA0900300),湖北省科技厅重大科技创新计划(2021BAD001) （22108064,21978071）
