医学信息2023，Vol.36Issue(23)：59-61,65,4.DOI:10.3969/j.issn.1006-1959.2023.23.014
心肌损伤标志物cTnⅠ、CK-MB、Hcy水平与冠状动脉粥样硬化的相关性
Correlation Between Myocardial Injury Markers cTnⅠ,CK-MB,Hcy Levels and Coronary Atherosclerosis
陆洋 1颜永进1
作者信息
- 1. 海安市人民医院心内科,江苏 海安 226600
- 折叠
摘要
Abstract
Objective To study the correlation between cardiac troponin Ⅰ(cTnⅠ),creatine kinase isoenzyme(CK-MB),homocysteine(Hcy)levels and coronary atherosclerosis(CAS).Methods A total of 120 CAS patients admitted to the Department of Cardiology,Hai'an People's Hospital from January 2019 to August 2021 were set as CAS group.According to their Gensini scores,they were divided into mild stenosis group(31 patients),moderate stenosis group(54 patients)and severe stenosis group(35 patients).According to the number of coronary artery lesions,they were divided into single-vessel disease group(44 patients)and multi-vessel disease group(76 patients).Another 100 healthy people in the same period were selected as the control group.The levels of cTnⅠ,CK-MB and Hcy in CAS group and control group and CAS group with different Gensini scores and lesion counts were compared.The correlation between the levels of cTnⅠ,CK-MB and Hcy and Gensini score and the number of lesions in CAS patients was analyzed.Results The levels of cTnⅠ,CK-MB and Hcy in the CAS group were higher than those in the control group(P＜0.05).The levels of cTnⅠ,CK-MB and Hcy from high to low were severe stenosis group＞moderate stenosis group＞mild stenosis group(P＜0.05).The levels of cTnI,CK-MB and Hcy in the multi-vessel disease group were higher than those in the multi-vessel disease group(P＜0.05).Pearson correlation analysis showed that the levels of cTnⅠ,CK-MB and Hcy were positively correlated with Gensini score and number of lesions in CAS patients(P＜0.05).Conclusion The levels of cTnⅠ,CK-MB and Hcy are closely related to the severity of CAS.关键词
冠状动脉粥样硬化/肌钙蛋白Ⅰ/肌酸激酶同工酶/同型半胱氨酸Key words
Coronary atherosclerosis/TroponinⅠ/Creatine kinase isoenzyme/Homocysteine分类
医药卫生引用本文复制引用
陆洋,颜永进..心肌损伤标志物cTnⅠ、CK-MB、Hcy水平与冠状动脉粥样硬化的相关性[J].医学信息,2023,36(23):59-61,65,4.
