医学信息2023，Vol.36Issue(23)：66-68,76,4.DOI:10.3969/j.issn.1006-1959.2023.23.016
马来酸曲美布汀与固本益肠片联合治疗肠易激综合征的临床效果
Clinical Effect of Trimebutine Maleate Combined with Guben Yichang Tablets in Treatment of Irritable Bowel Syndrome
韩付金 1张静 1张鸿博1
作者信息
- 1. 天津市宁河区中医医院消化科,天津 301500
- 折叠
摘要
Abstract
Objective To study the clinical effect of trimebutine maleate combined with Guben Yichang TAblets in treatment of irritable bowel syndrome(IBS).Methods Forty patients with IBS admitted to Tianjin Ninghe District Hospital of Traditional Chinese Medicine from January 2020 to June 2021 were selected and divided into control group(20 patients)and observation group(20 patients)by random number table method.The control group was treated with trimebutine maleate,and the observation group was treated with Guben Yichang tablets on the basis of trimebutine maleate.The severity score of irritable bowel syndrome(IBS-SSS scale),TCM symptom score,clinical efficacy,diarrhea,abdominal pain response rate and adverse reactions were compared between the two groups.Results After treatment,the IBS-SSS score and TCM symptom score of the observation group were lower than those of the control group(P＜0.05).The total effective rate of treatment in the observation group was 95.00%,which was higher than 75.00%in the control group(P＜0.05).The response rate of diarrhea and abdominal pain in the observation group was higher than that in the control group at 4 weeks after treatment(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Trimebutine maleate combined with Guben Yichang tablets is effective in the treatment of IBS,which can improve the clinical symptoms of patients,improve the response of diarrhea and abdominal pain,and is safe and feasible.关键词
马来酸曲美布汀/肠易激综合征/固本益肠片/腹泻应答/不良反应Key words
Trimebutine maleate/Irritable bowel syndrome/Guben Yichang tablets/Diarrhea response/Adverse reactions分类
医药卫生引用本文复制引用
韩付金,张静,张鸿博..马来酸曲美布汀与固本益肠片联合治疗肠易激综合征的临床效果[J].医学信息,2023,36(23):66-68,76,4.
