摘要
Abstract
Objective To study the therapeutic effect of anti-vascular endothelial growth factor(VEGF)drugs on retinal vein occlusion(RVO).Methods Thirty-five RVO patients(35 eyes)admitted to the Department of Ophthalmology,Nanjing Gaochun People's Hospital from June 2020 to September 2022 were selected as the research objects.According to the pathological classification,they were divided into ischemic type(18 patients)and non-ischemic type(17 patients).According to the site of vascular obstruction,they were divided into 16 patients of central retinal vein occlusion(CRVO)and 19 patients of branch retinal vein occlusion(BRVO).They were treated with anti-VEGF drugs by intraocular injection.The best corrected visual acuity(BCVA)and optical coherence tomography(OCT)indexes[central macular thickness(CMT),subfoveal choroidal thickness(SFCT),choroidal vascular index(CVI)]of patients with different types of RVO before and after treatment were compared.Results The BCVA of patients with ischemic and non-ischemic RVO after treatment was higher than that before treatment,and CMT,SFCT and CVI were lower than those before treatment,while the BCVA of patients with non-ischemic RVO was higher than that of patients with ischemic RVO,and CMT,SFCT and CVI were lower than those of patients with ischemic RVO(P＜0.05).The BCVA of CRVO and BRVO patients after treatment was higher than that before treatment,and CMT,SFCT and CVI were lower than those before treatment.The BCVA of BRVO patients was higher than that of CRVO patients,and CMT,SFCT and CVI were lower than those of CRVO patients(P＜0.05).Conclusion Anti-VEGF drugs have good therapeutic effects in patients with different types of RVO,but they have more clinical benefits for patients with non-ischemic RVO and BRVO.关键词
视网膜静脉阻塞/抗血管内皮生长因子药物/最佳矫正视力/脉络膜血管指数Key words
Retinal vein occlusion/Anti-vascular endothelial growth factor drugs/Best corrected vision/Choroidal vascular index分类
医药卫生
