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代谢相关脂肪性肝病发病机制的研究

胡丽平 蔡华 李情娇 唐璐

医学信息2023,Vol.36Issue(23):174-179,6.
医学信息2023,Vol.36Issue(23):174-179,6.DOI:10.3969/j.issn.1006-1959.2023.23.044

代谢相关脂肪性肝病发病机制的研究

Study on the Pathogenesis of Metabolism Associated Fatty Liver Disease

胡丽平 1蔡华 2李情娇 3唐璐4

作者信息

  • 1. 湖南师范大学附属第一医院/湖南省人民医院重症医学科 湖南 长沙 410000
  • 2. 湖南师范大学附属第一医院/湖南省人民医院临床营养科,湖南 长沙 410000
  • 3. 湖南师范大学附属第一医院/湖南省人民医院康复医学科,湖南 长沙 410000
  • 4. 湖南师范大学附属第一医院/湖南省人民医院介入血管外科,湖南 长沙 410000
  • 折叠

摘要

Abstract

In recent years,with the rapid development of China's economy and unhealthy people's living habits,the incidence of metabolic associated fatty liver disease(MAFLD)is increasing and getting younger.With the prevalence of obesity and metabolic syndrome,MAFLD has become the largest liver disease in China.Although the pathogenesis of MAFLD is still unclear,its occurrence and development are strongly associated with metabolic syndrome,and MAFLD is the main manifestation of metabolic syndrome in the liver.Adipose tissue has a significant impact on metabolic syndrome,it can not only store quantity,but also have endocrine function and can secretes different adipokines.The imbalance and dysfunction of adipokine secretion can lead to the occurrence of metabolic diseases such as MAFLD.Therefore,this paper reviews the recent advances in the study of metabolic associated fatty liver disease and adipokines as follows,providing possibilities for the study of new drugs.

关键词

代谢相关脂肪性肝病/脂肪因子/瘦素/脂联素

Key words

Metabolism associated fatty liver disease/Adipocytokines/Leptin/Adiponectin

分类

医药卫生

引用本文复制引用

胡丽平,蔡华,李情娇,唐璐..代谢相关脂肪性肝病发病机制的研究[J].医学信息,2023,36(23):174-179,6.

基金项目

湖南省卫生健康委科研计划项目(编号:202203033572) (编号:202203033572)

医学信息

1006-1959

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