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生长激素激发试验和胰岛素样生长因子1水平检测对生长激素缺乏症的诊断意义和思考

李堂

中国当代儿科杂志2023,Vol.25Issue(12):1193-1197,5.
中国当代儿科杂志2023,Vol.25Issue(12):1193-1197,5.DOI:10.7499/j.issn.1008-8830.2308076

生长激素激发试验和胰岛素样生长因子1水平检测对生长激素缺乏症的诊断意义和思考

Diagnostic significance and considerations of growth hormone stimulation testing and insulin-like growth factor 1 in growth hormone deficiency

李堂1

作者信息

  • 1. 青岛大学附属妇女儿童医院儿童内分泌代谢科,山东青岛 266000
  • 折叠

摘要

Abstract

The growth hormone(GH)/insulin-like growth factor 1(IGF-1)axis is an essential component of the hypothalamic-pituitary growth hormone axis and plays a crucial role in childhood growth and development.Disruptions and abnormalities in the GH/IGF-1 signaling pathway and its pathways typically manifest as short stature in children.Children with short stature often undergo GH stimulation testing and IGF-1 level measurements to differentiate growth hormone deficiency(GHD)from other causes of growth delay.This article aims to analyze and elucidate the values of GH stimulation testing and IGF-1 measurement,providing reference for the diagnosis of GHD in children.

关键词

生长激素缺乏症/生长激素/胰岛素样生长因子1/生长激素激发试验/儿童

Key words

Growth hormone deficiency/Growth hormone/Insulin-like growth factor 1/Growth hormone stimulation testing/Child

引用本文复制引用

李堂..生长激素激发试验和胰岛素样生长因子1水平检测对生长激素缺乏症的诊断意义和思考[J].中国当代儿科杂志,2023,25(12):1193-1197,5.

中国当代儿科杂志

OA北大核心CSCDCSTPCDMEDLINE

1008-8830

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