中国当代儿科杂志2023，Vol.25Issue(12)：1239-1245,7.DOI:10.7499/j.issn.1008-8830.2307034
辅助生殖技术对双胎出生体重不一致的影响
Impact of assisted reproductive technology on birth weight discordance in twins
摘要
Abstract
Objective To explore the association between assisted reproductive technology(ART)and birth weight discordance in twins(BWDT).Methods A retrospective analysis was conducted on twin infants born between January 2011 and December 2020 at the Third Affiliated Hospital of Guangzhou Medical University,with complete basic birth data.The impact of ART on the occurrence of BWDT was identified by the multivariate logistic regression analysis.Results A total of 3 974 pairs of twins were included,with 1 431 conceived naturally and 2 543 through ART.Neonates in the ART group had higher birth weights than those in the naturally conceived group(P<0.001).The incidence of BWDT was lower in the ART group compared to the naturally conceived group(16.17%vs 21.09%,P<0.001).The multivariate logistic regression analysis,adjusting for confounding factors such as maternal age,parity,pre-pregnancy body mass index,gestational diabetes,hypothyroidism,gestational age,and chorionic properties,showed no significant difference in the risk of BWDT between the ART and naturally conceived groups(P>0.05).Conclusions ART is not associated with the risk of BWDT.关键词
出生体重不一致/辅助生殖/双胎/新生儿Key words
Birth weight discordance/Assisted reproductive technology/Twins/Neonate引用本文复制引用
李秋影,张慧,陈倩,石碧君,谭小华,崔其亮..辅助生殖技术对双胎出生体重不一致的影响[J].中国当代儿科杂志,2023,25(12):1239-1245,7.基金项目
广东省医学科研基金(B2019018) （B2019018）
广州市卫生健康科技项目西医类一般引导项目(20231A011087、20231A011093) （20231A011087、20231A011093）
儿童生长发育专科重点学科建设——高危儿生长发育促进及综合管理模式构建的研究(20230704). （20230704）
