中国当代儿科杂志2023，Vol.25Issue(12)：1246-1252,7.DOI:10.7499/j.issn.1008-8830.2307040
大于胎龄儿12月龄神经心理发育状况研究
Neuropsychological development of large for gestational age infants at the age of 12 months
包梦雨 1乔秀芸 2张新涵 1张子璇 1赵菲 1陈新霞1
作者信息
- 1. 山东大学护理与康复学院,山东济南 250012
- 2. 山东第一医科大学第一附属医院/山东省千佛山医院护理部,山东济南 250013
- 折叠
摘要
Abstract
Objective To investigate the level of neuropsychological development in large for gestational age(LGA)infants at the age of 12 months.Methods The infants,aged 12 to<13 months,who attended the Outpatient Service of Child Care in the First Affiliated Hospital of Shandong First Medical University from December 2021 to June 2023,were enrolled as subjects.According to the gestational age and birth weight,they were divided into preterm appropriate for gestational age(AGA)group,preterm LGA group,early term AGA group,early term LGA group,full-term AGA group,and full-term LGA group.A modified Poisson regression analysis was used to investigate the association between LGA and neuropsychological development outcome at 12 months of age.Results After adjustment for confounding factors,compared with the full-term AGA group at the age of 12 months,the full-term LGA group had a significant increase in the risk of language deficit(RR=1.364,95%CI:1.063-1.750),the early term LGA group had significant increases in the risk of abnormal gross motor,fine motor,language,and the preterm LGA group had significant increases in the risk of abnormal language,social behavior,and total developmental quotient(P<0.05);also,the early term AGA group had higher risks of developmental delay across all five attributes and in total developmental quotient at the age of 12 months(P<0.05);except for the language attribute,the preterm AGA group had higher risks of developmental delay in the other 4 attributes(P<0.05).Conclusions The neuropsychological development of LGA infants with different gestational ages lags behind that of full-term AGA infants at 12 months of age,and follow-up and early intervention of such infants should be taken seriously in clinical practice.关键词
大于胎龄儿/神经心理发育/早产儿/早期足月儿/完全足月儿Key words
Large for gestational age infant/Neuropsychological development/Preterm infant/Early term infant/引用本文复制引用
包梦雨,乔秀芸,张新涵,张子璇,赵菲,陈新霞..大于胎龄儿12月龄神经心理发育状况研究[J].中国当代儿科杂志,2023,25(12):1246-1252,7.
