中国动脉硬化杂志2023，Vol.31Issue(11)：921-928,8.DOI:10.20039/j.cnki.1007-3949.2023.11.001
动脉粥样硬化危险因素衰老、肥胖、生物钟紊乱与核糖体新生的研究进展
Research progress of atherosclerosis risk factors like aging,obesity,circadian clock disorders and ribosome biogenesis
摘要
Abstract
Atherosclerosis is the leading cause of cardiovascular and cerebrovascular diseases caused by smoking,hypertension,aging,obesity,circadian clock disorders,and other factors.As a molecular machine for protein synthesis,ribosomes maintain protein homeostasis in cells.This review focuses on the impact of aging,obesity,and circadian clock disorders on the development of atherosclerosis and the relationship with ribosome biogenesis and provides the theoretical basis for both basic research and clinical intervention of atherosclerosis.关键词
动脉粥样硬化/核糖体新生/衰老/肥胖/生物钟紊乱Key words
atherosclerosis/ribosome biogenesis/aging/obesity/circadian clock disorder分类
医药卫生引用本文复制引用
张瑜,涂均楚,李玉洁,吴伟亮,韩青芳,焦丽娟,王燕丽,李杨欣..动脉粥样硬化危险因素衰老、肥胖、生物钟紊乱与核糖体新生的研究进展[J].中国动脉硬化杂志,2023,31(11):921-928,8.基金项目
国家自然科学基金面上项目(82370264和81870194) （82370264和81870194）
国家自然科学基金重大研究计划项目(91849122) （91849122）
江苏省"六大人才高峰"创新团队项目(BU24600117) （BU24600117）
中国博士后基金(2021M702394) （2021M702394）
江苏省卓越博士后项目 （）
放射医学与辐射防护国家重点实验室资助项目(GZK12023023) （GZK12023023）
