中国动脉硬化杂志2023，Vol.31Issue(11)：995-1000,6.DOI:10.20039/j.cnki.1007-3949.2023.11.010
肠道菌群对动脉粥样硬化性心血管疾病发病影响的研究进展
Research progress of the effect of intestinal flora on the pathogenesis of atherosclerotic cardiovascular disease
摘要
Abstract
Artery stenosis due to atherosclerosis is the most common cause of cardiovascular disease.In addition to known risk factors,researchers have found that intestinal flora can influence the pathogenesis of atherosclerosis through its metabolites(short-chain fatty acids,trimethylamine oxide,indoles),the metabolism of bile acids,and the inflammatory response,and the relevant evidence has been supported experimentally.This article presents a systematic review of the relationship between intestinal flora and atherosclerotic cardiovascular disease,the microscopic mechanisms by which intes-tinal flora affect the pathogenesis of atherosclerotic cardiovascular disease,and recent advances in the treatment of athero-sclerotic cardiovascular disease using intestinal flora as a target.关键词
肠道菌群/动脉粥样硬化性心脏病/代谢产物/作用机制/治疗方法Key words
intestinal flora/atherosclerotic cardiovascular disease/metabolite/mechanism of action/treat-ment method分类
医药卫生引用本文复制引用
翟佳诚,王婷,刘富强,王军奎..肠道菌群对动脉粥样硬化性心血管疾病发病影响的研究进展[J].中国动脉硬化杂志,2023,31(11):995-1000,6.基金项目
陕西省重点研发计划重点产业创新链(2021ZDLSF02-03) （2021ZDLSF02-03）
