中国临床医学影像杂志2023，Vol.34Issue(12)：851-855,5.DOI:10.12117∕jccmi.2023.12.004
基于MRI联合特征鉴别鼻腔鼻窦恶性黑色素瘤与鳞癌
Differentiation of sinonasal malignant melanoma and squamous cell carcinoma based on MRI combined features
摘要
Abstract
Objective:Sinonasal malignant melanoma is easily misdiagnosed as squamous cell carcinoma,but the treatment methods are different.Therefore,this study explores MRI features of sinonasal malignant melanoma as compared with squa-mous cell carcinoma.Methods:Retrospective analysis was conducted for 122 patients with complete clinical and MRI data,confirmed by surgery and pathology,including 69 cases with sinonasal malignant melanoma(SMM)and 53 patients with squa-mous cell carcinoma(SCC).We compare the differences of MRI features between SMM and SCC.The logistic regression analy-sis was performed to identify the most discriminating MRI features.And the sensitivity,specificity,and accuracy of diagnosing malignant melanoma were analyzed by receiver operating characteristic(ROC)curve.The model of multiple parameters was es-tablished by logistic analysis,and the diagnostic efficacy was evaluated.Results:The gender,tumor location,shape,hyperin-tense on T1WI,hypointense on T2WI,septate pattern on T1WI(T1-SP),necrosis,orbital involvement and cheek soft tissue in-volvement were significantly different between sinonasal malignant melanoma and squamous cell carcinoma(P<0.05).Logistic re-gression analysis showed mass shape,hyperintense on T1WI,T1-SP and necrosis were the independent influencing factor of sinonasal malignant melanoma,hyperintense on T1WI has the highest accuracy,which is 83.6%.The sensitivity,specificity and accuracy of the combination of mass shape,hyperintense on T1WI,T1-SP and necrosis were 85.5%,90.6%and 86.9%,re-spectively.The diagnostic performance of combination features was higher than that of each single sign(P<0.001).Conclusion:MRI features are helpful to distinguish sinonasal malignant melanoma from squamous cell carcinoma.The logistic regression model helps to improve the diagnostic rate of sinonasal malignant melanoma,providing evidence for clinical diagnosis.关键词
鼻肿瘤/黑色素瘤/磁共振成像Key words
Nose Neoplasms/Melanoma/Magnetic Resonance Imaging分类
医药卫生引用本文复制引用
郑璇,赵会军,王新艳,张涵娟,彭如臣,鲜军舫..基于MRI联合特征鉴别鼻腔鼻窦恶性黑色素瘤与鳞癌[J].中国临床医学影像杂志,2023,34(12):851-855,5.基金项目
北京市医院管理中心"登峰"计划专项经费资助(编号:DFL20190203). （编号:DFL20190203）
