中国全科医学2024，Vol.27Issue(9)：1021-1027,7.DOI:10.12114/j.issn.1007-9572.2023.0525
精神分裂症的社区治疗获益:基于长效注射用抗精神病药物
Benefits of Community-based Treatment for Patients with Schizophrenia:Based on Long-acting Injectable Antipsychotic Agents
摘要
Abstract
Schizophrenia could affect the social and occupational functions of patients in the long term.Community-based mental health services and management models promote mental health by improving accessibility,acceptability,affordability,practicality and scalability.In the community management model,long-acting injectable antipsychotic agents are one of the main strategies for the treatment of schizophrenia,but there is a lack of relevant evidence.This paper systematically and comprehensively discussed the benefits of long-acting injectable antipsychotic agents in patients with schizophrenia,including effectiveness and safety,compliance,attitude to use,social function recovery and community rehabilitation.The results of this study showed that long-acting injectable antipsychotic agents can exert superior efficacy than oral drugs in the community rehabilitation of schizophrenia patients under different community management modes,not only reflected in the disease recurrence rate and readmission rate,but also in the recovery of social functioning and the reduction of accident rate and other aspects of excellent performance.However,the overall prescription rate of long-acting injectable antipsychotic agents is still low in China.The main reasons include insufficient information sharing between medical institutions and communities in primary level,low community medical services and treatment rate,low follow-up rate of patients,and less community psychiatric rehabilitation.This study can provide some references for the community treatment of schizophrenia patients in China,explore more community treatment programs,and improve the treatment effect and quality of life of schizophrenia patients in China.关键词
精神分裂症/抗精神病药/长效制剂/长效注射用抗精神病药物/社区治疗/获益/用药依从性Key words
Schizophrenia/Antipsychotic agents/Depot preparation/Long-acting injectable antipsychotic agents/Community treatment/Benefits/Medication adherence分类
医药卫生引用本文复制引用
中华医学会精神医学分会精神分裂症协作组,中华医学会全科医学分会,李茜,司天梅..精神分裂症的社区治疗获益:基于长效注射用抗精神病药物[J].中国全科医学,2024,27(9):1021-1027,7.基金项目
首都卫生发展科研专项重点攻关项目(2022-1-4111) （2022-1-4111）
