摘要
Abstract
Objective To investigate the HBV infection markers detection and demographic characteristics of first-time blood donors,so as to provide evidence for blood donor recruitment.Methods HBsAg was detected by ELISA,HBsAg neg-ative samples were tested for HBV DNA,and chemiluminescence method was used to detect HBsAg,HBsAb,HBcAb,HBeAg and HBeAb in first-time blood donor HBsAg-/HBV DNA+samples.Demographic information of HBsAg positive first-time donors was analyzed.Results From 2018 to 2022,a total of 502 739 people participated in voluntary blood dona-tion,and first-time blood donors accounted for 33.79%.The HBsAg positive rate of first-time donors(28.37/10 000,482/169 897)was higher than that of repeated blood donors(3.46/10 000,115/332 842)(OR=8.23,95% CI:6.72～10.09),and the HBV DNA positive rate of first-time blood donors(4.83/10 000,82/169 897)was lower than that of repeated blood donors(6.52/10 000,217/332 842)(OR=0.74,95% CI:0.57～0.95).The positive rate of HBcAb in HBsAg-/HBV DNA+samples of first-time blood donors was 73.17%.Significant differences were noticed in HBsAg-/HBV DNA+and HBsAg pos-itive rate among first-time blood donors among gender,age,education background and occupation(all P＜0.05).Conclusion Low risk first-time blood donor recruitment is important for blood donation.Strengthening HBV screening before blood do-nation and detection after blood donation is beneficial to improve the safety of blood transfusion.关键词
首次献血者/招募/HBsAg/HBV DNA/HBcAbKey words
first-time blood donors/recruitment/HBsAg/HBV DNA/HBcAb分类
医药卫生
