中国输血杂志2023，Vol.36Issue(11)：1025-1028,4.DOI:10.13303/j.cjbt.issn.1004-549x.2023.11.013
去白细胞混合浓缩血小板制备的质量控制及临床应用效果观察
Preparation quality control and clinical application observation of pooled platelets with leukocytes reduced
摘要
Abstract
Objective To investigate the preparation quality and clinical application effect of pooled platelets with leuko-cytes reduced.Methods The quality and clinical effect of the buffy-coated method prepared pooled platelets leukocytes re-duced(experimental group,n=40)and apheresis platelets leukocytes reduced(control group,n=40)were compared.Re-sults The platelet volume(mL),platelet count(×1011),red blood cell contamination(×108)and residual white blood cell(×106)of the experimental group and control group were 278.90±7.92 vs 276.52±8.01,2.66±0.09 vs 2.66±0.83,0.54±0.42 vs 0.83±0.84,0.29±0.54 vs 0.27±0.51,respectively,with no significant difference.The results of bacterial culture were negative,all met the requirements of relevant national standards.In addition,the CCI(×103,24 h)and PPR(%)were 15.11±9.86 vs 14.61±12.55 and 54.23±18.70 vs 61.41±19.09 respectively,with no significant difference,indicating a certain degree of therapeutic effect.Conclusion The quality and clinical therapeutic effect of pooled platelets leukocytes re-duced were consistent with that of apheresis platelets leukocytes reduced.关键词
去白细胞混合浓缩血小板/去白细胞单采血小板/应用效果Key words
pooled platelets leukocytes reduced/apheresis platelets leukocytes reduced/application effect分类
医药卫生引用本文复制引用
郭敏,和苗,杨文娟,李建民,刘建辉,杨宁,张静,李玉秋,程菲,刘旭枝,贺强..去白细胞混合浓缩血小板制备的质量控制及临床应用效果观察[J].中国输血杂志,2023,36(11):1025-1028,4.基金项目
河北省医学科学研究课题计划指令性课题(20231233) （20231233）
