中国输血杂志2023，Vol.36Issue(11)：1029-1032,4.DOI:10.13303/j.cjbt.issn.1004-549x.2023.11.014
单采富血小板血浆采集相关不良事件分析及应对策略
Adverse events in platelet-rich plasma collection and countermeasures
摘要
Abstract
Objective To explore the quality of platelet-rich plasma(PRP)and adverse events during PRP collection and the countermeasures,so as to provide reference for the development of PRP therapy.Methods A total of 412 patients who underwent PRP treatment from November 2020 to October 2022 were statistically analyzed in terms of the general data,PRP quality and adverse events during collection,and the countermeasures were formulated.Results PRP was collected from 409 patients with a volume of(48.391±6.262)mL,with platelet concentration at(1 125.548±366.036)×109/L.There were 33 adverse events occurred in 412 patients,with an incidence of 8.01%(33/412),among which 10 was regarding to collection and 23 were adverse reaction to blood donation.The reasons include mental factors,hyperlipidemia,hypovolemia,abnormal red blood cell morphology and venous puncture injury.Conclusion Countermeasures against the relative risk fac-tors of adverse events during PRP collection,such as exclusion of hyperlipidemia,relieving mental stress,providing ade-quate communication and water to patients with low body weight,lowering the collection and transfusion flow rate to patients with poor vascular status and providing calcium gluconate to patients with low calcium response should be taken.关键词
富血小板血浆/不良事件/不良反应/应对策略Key words
platelet-rich plasma(PRP)/adverse events/adverse reaction/countermeasures分类
医药卫生引用本文复制引用
王文婷,郑妍,李颖,穆士杰..单采富血小板血浆采集相关不良事件分析及应对策略[J].中国输血杂志,2023,36(11):1029-1032,4.基金项目
军委后勤保障部卫生局卫勤保障能力创新与生成专项项目(21WQ28) （21WQ28）
唐都医院科技创新项目(2019LCYJ017) （2019LCYJ017）
