摘要
Abstract
Objective To investigate the variation of hematological parameters in male plateletpheresis donors.Methods A total of 194 male plateletpheresis donors from Fujian Blood Center were divided into two groups according to the frequen-cy of blood donation:Group 1(n= 107),with the number of plateletpheresis donation less than or equal to 12 per year;Group 2(n=87),with the number of plateletpheresis donation more than 12 per year.Serum ferritin(SF)and related iron metabolism indexes,red blood cell count(RBC),hemoglobin(Hb),hematocrit(Hct),platelet count(Plt)and other blood routine indexes,as well as percentage of reticulocyte counts(RET%),immature reticulocyte fraction(IRF)and other reticulocyte indexes were measured before blood donation and analyzed by statistical methods.Results Compared with Group 2,the RBC,Hb,Hct,SF in Group 1 were significantly higher,while Plt,RET% and IRF were significantly lower(P＜0.05),and the probability of ferritin decrease in Group 1 was lower,with significant difference(P＜0.05).Conclusion As the number of donation increased,male plateletpheresis donors were prone to iron deficiency,and the bone marrow hematopoiesis were obviously enhanced.We should be more concerned about male plateletpheresis donors who donated more than 12 times per year,further more,SF monitoring should be conducted and the blood donation interval should be appropriately extended.关键词
单采献血者/铁代谢/网织红细胞参数Key words
plateletpheresis donors/iron metabolism/reticulocyte parameters分类
医药卫生
