中国输血杂志2023，Vol.36Issue(11)：1064-1067,4.DOI:10.13303/j.cjbt.issn.1004-549x.2023.11.023
免疫性溶血性输血反应的鉴定分析及输血相容性检测探讨
Identification of immune hemolytic transfusion reaction and exploration of transfusion compatibility testing
焦秀娟 1刘专 1黄宏亮1
作者信息
- 1. 盐城市中心血站,江苏 盐城 224005
- 折叠
摘要
Abstract
Objective To analyze the causes of immune hemolytic transfusion reaction in one case,identify related anti-bodies,and explore transfusion compatibility testing.Methods ABO/Rh blood group identification,unexpected antibody i-dentification of serum and diffusion fluid,direct antiglobulin test(DAT)and cross matching were conducted by saline method and/or microcolumn gel method.Results The patient's blood group was O,and Rh phenotype was identified as DCCee.The DAT was negative,with strong anti-E antibody and weak anti-c antibody detected.Acute hemolytic transfusion reaction oc-curred in the patient after the last transfusion.Conclusion Currently,immune hemolytic transfusion reaction in China are mainly caused by Rh blood group system antibodies.The absence of unexpected antibody screening before blood transfusion and the weak anti-c antibody which resulted in missed detection of non compatibility in cross matching led to acute hemolytic transfusion reaction.It is recommended to conduct unexpected antibody screening before blood transfusion,and to collect blood sample for testing as soon as possible to improve the accuracy of DAT when acute hemolytic transfusion reaction is sus-pected.关键词
溶血性输血反应/Rh血型/不规则抗体/抗-E/抗-cKey words
hemolytic transfusion reaction/Rh blood group/unexpected antibody/anti-E/anti-c分类
医药卫生引用本文复制引用
焦秀娟,刘专,黄宏亮..免疫性溶血性输血反应的鉴定分析及输血相容性检测探讨[J].中国输血杂志,2023,36(11):1064-1067,4.
