中国医学伦理学2023，Vol.36Issue(12)：1330-1335,6.DOI:10.12026/j.issn.1001-8565.2023.12.06
脑类器官研究进展和伦理问题研究
Research Progress and Ethical Issues of Brain Organoids
摘要
Abstract
Organoids are three-dimensional(3D)biological structures constructed in vitro by stem cells,which partially mimic the function of real organs.Brain organoids are an extremely important branch of organoid research.This technology can differentiate pluripotent stem cells into the required cell types in a 3D culture environment,and self-assemble into structural bodies,but it is currently unable to fully replicate the structural and physiological features of the real human brain.The maturity of brain organoids may form consciousness,which poses ethical issues such as determining moral status and informed consent in brain organoids research.This paper elaborated on the research progress and future development direction of brain organoids,and proposed multidimensional governance strategies for ethical issues faced in brain organoids research from the perspectives of ethical principles,ensuring public informed consent,and legal supervision.By exploring the above issues,reference will be provided for formulating ethical principles to guide the research and application of brain organoids in the future.关键词
神经伦理学/脑类器官/类器官/道德地位Key words
Neuroethics/Brain Organoids/Organoids/Moral Status分类
医药卫生引用本文复制引用
方彩霞,王振运,白晓东..脑类器官研究进展和伦理问题研究[J].中国医学伦理学,2023,36(12):1330-1335,6.基金项目
甘肃省科技计划项目"胆道系统疾病与轻度认知功能障碍相关性研究"(21JRRM908) （21JRRM908）
庆阳市科技计划项目"胆汁淤积与轻度认知功能障碍相关性研究"(QY2021A-S031) （QY2021A-S031）
庆阳市科技创新平台与人才计划"庆阳市心脑血管疾病临床医学研究中心"(庆财市教[2022]42号-33) （庆财市教[2022]42号-33）
