中国现代医生2023，Vol.61Issue(34)：5-8,4.DOI:10.3969/j.issn.1673-9701.2023.34.002
CONUT评分对初诊类风湿关节炎患者病情严重程度的评估价值
The evaluation value of CONUT score for severity of newly diagnosed rheumatoid arthritis
摘要
Abstract
Objective To investigate the value of controlling nutritional status(CONUT)score in evaluating the severity of newly diagnosed rheumatoid arthritis(RA).Methods The clinical data of 303 newly diagnosed RA patients treated in Huzhou Central Hospital from January 2020 to February 2023 were retrospectively analyzed.Patients were divided into low activity group(n=106)and medium high activity group(n=197)according to different disease activity levels.The clinical data and laboratory examination indexes of two groups were collected and compared.Receiver operating characteristic(ROC)curve was drawn to analyze the diagnostic efficacy of CONUT score on the activity of RA patients and determine the optimal critical value.The clinical characteristics of RA patients with different CONUT score were compared.Results The hypersensitive C-reaction protein,white blood cell count,platelet count,erythrocyte sedimentation rate,rheumatoid factor,globulin,disease activity score 28 joints C-reactive protein and the proportion of diabetes mellitus and hypertension in medium high activity group were significantly higher than those in low activity group(P<0.05),and the hemoglobin was significantly lower than that in low activity group(P<0.05).The ROC curve results showed that the area under the curve of CONUT score to distinguish the activity of RA patients was 0.872,and the sensitivity and specificity were 88.3%and 72.6%,respectively.There were significant differences in disease activity,bone mineral density,organ/system involvement and disease course among patients with different CONUT score(P<0.05).Patients with higher CONUT score had more severe disease.Conclusion CONUT score has a certain diagnostic value for disease activity in RA patients,and CONUT score can be used as an evaluation index for disease severity of RA.关键词
类风湿关节炎/控制营养状态评分/疾病活动度Key words
Rheumatoid arthritis/Controlling nutritional status score/Disease activity分类
医药卫生引用本文复制引用
殷丽娟..CONUT评分对初诊类风湿关节炎患者病情严重程度的评估价值[J].中国现代医生,2023,61(34):5-8,4.基金项目
浙江省医药卫生科技计划项目(2022RC073) （2022RC073）
