中国现代医生2023，Vol.61Issue(34)：34-36,3.DOI:10.3969/j.issn.1673-9701.2023.34.009
二胺氧化酶对溃疡性结肠炎病情评估的价值研究
Study on the value of diamine oxidase in the evalution of ulcerative colitis
仝建军 1薛建波 1刘红巧 2张雷3
作者信息
- 1. 首都医科大学大兴医院消化科,北京 102600
- 2. 首都医科大学大兴医院体检中心,北京 102600
- 3. 首都医科大学大兴医院检验科,北京 102600
- 折叠
摘要
Abstract
Objective To investigate the value of peripheral blood diamine oxidase(DAO)in evaluating the severity of ulcerative colitis(UC).Methods A total of 76 UC patients admitted to Daxing Hospital,Capital Medical University from June 2020 to June 2022 were included in UC group,and were divided into severe ulcerative colitis(SUC)group and non-SUC group according to the severity of the disease.A total of 76 healthy subjects were included as control group.The general data and serum DAO of all subjects were collected for statistical analysis.Results The serum DAO level in UC group was significantly higher than that in control group(P<0.05).The serum DAO level in SUC group was significantly higher than that in non-SUC group(P<0.05).Receiver operating characteristic curve analysis showed that DAO predicted area under the curve(AUC)of UC was 0.751(95%CI:0.672-0.829,P<0.001),and DAO predicted AUC of SUC was 0.866(95%CI:0.807-0.925,P<0.001).Conclusion Serum DAO is an effective test index for evaluating the severity of UC,which is worthy of clinical promotion.关键词
二胺氧化酶/溃疡性结肠炎/肠道黏膜屏障/病情评估Key words
Diamine oxidase/Ulcerative colitis/Intestinal mucosal barrier/Disease assessment分类
医药卫生引用本文复制引用
仝建军,薛建波,刘红巧,张雷..二胺氧化酶对溃疡性结肠炎病情评估的价值研究[J].中国现代医生,2023,61(34):34-36,3.
