摘要
Abstract
Objective To investigate effect of Nd:YAP laser combined with periodontal basic treatment on periodontal indexes,subgingival microflora,adiponectin,matrix metalloproteinase-13(MMP-13),interleukin-6(IL-6)in gingival crevicular fluid in patients with periodontitis.Methods A total of 162 patients with periodontitis diagnosed and treated in the First People's Hospital of Huzhou from January 2020 to December 2021 were selected and divided into experimental group(n=55),basic group(n=54)and control group(n=53)by random number table method.The basic group received periodontal basic treatment,the control group was given Nd:YAP laser treatment,and the experimental group was given Nd:YAP laser combined with periodontal basic treatment.The clinical efficacy,probing depth(PD),bleeding index(BI),clinical attachment loss(CAL),plaque index(PLI),subgingival microflora,adiponectin,MMP-13 and IL-6 levels in gingival creval fluid and the incidence of complications were compared among three groups.Results At 6 weeks after treatment,there was significant difference in the total effective rate among three groups(P<0.05),and experimental group>control group>basic group.At 6 weeks after treatment,PD,CAL,BI,PLI,bacteroides,clostridium,lactobacillus,MMP-13 and IL-6 in three groups were significantly lower than before treatment,and adiponectin were significantly higher than before treatment(P<0.05).PD,CAL,BI,PLI,bacteroides,clostridium,lactobacillus,MMP-13 and IL-6 in experimental group were significantly lower than those in control group and basic group,and adiponectin was significantly higher than that in control group and basic group(P<0.05).There was no significant difference in the incidence of adverse reactions among three groups(P>0.05).Conclusion Nd:YAP laser combined with periodontal basic treatment has a good therapeutic effect on periodontitis,which can improve periodontal indexes,subgingival microflora,and adiponectin,MMP-13 and IL-6 in gingival crevicular fluid.关键词
Nd:YAP激光/牙周基础治疗/牙周炎/牙周指标/龈下菌群/脂联素/基质金属蛋白酶13/白细胞介素-6Key words
Nd:YAP laser/Periodontal basic treatment/Periodontitis/Periodontal index/Subgingival microflora/Adiponectin/Matrix metalloproteinase-13/Interleukin-6分类
医药卫生
