滨州医学院学报2023，Vol.46Issue(6)：434-437,4.DOI:10.19739/j.cnki.issn1001-9510.2023.06.008
胃癌术后患者肠内营养不耐受的相关因素分析
Analysis of related factors of enteral nutrition intolerance in patients with gastric cancer after surgery
摘要
Abstract
Objective To investigate the influencing factors of enteral nutritional intolerance in patients with gastric cancer after surgery.Methods Ninety-nine patients with gastric cancer undergoing enteral nutrition therapy were enrolled.Nutrient so-lutions(glutamine,Peptisorb,Kangquali,and Ruixian)were used according to the patient's postoperative recovery of gastroin-testinal function.Among them,saline(0.9%concentration)was used before enteral nutrition in 54 cases.According to whether patients had symptoms of intolerance after surgery,they were divided into the tolerance group and the intolerance group.The symptoms of the intolerance group(nausea and vomiting,abdominal pain,bloating,diarrhea),the first time to get out of bed af-ter surgery and the time to first use enteral nutrition,as well as the changes in biochemical indexes(total protein,albumin)be-fore and after the use of enteral nutrition were observed.Results Intolerance was developed in 40 patients,including 32 cases of abdominal distention,22 cases of abdominal pain,8 cases of diarrhea,and 8 cases of nausea and vomiting.There were 59 cases without intolerance symptoms.Intolerance was developed in 25 patients with Peptisorb,14 with glutamine,and 2 with Kangquan-li.There were significant differences in intraoperative blood loss,postoperative first time out of bed and actual enteral nutrition dosage in the enteral nutrition-tolerant group(P＜0.05).Absolute lymphocyte values and total protein were elevated in all pa-tients(P＜0.05).The albumin in the tolerant group was elevated and the difference was statistically significant(P＜0.05).The results of multivariate logistic analysis showed that intraoperative bleeding(OR=1.018)was an independent risk factor for enteral nutritional intolerance in patients with gastric cancer.Conclusion High actual infusion of enteral nutrition and intraoper-ative bleeding in gastric cancer patients are risk factors for intolerance of EN,which will delay postoperative recovery.关键词
胃癌术后/肠内营养/耐受性Key words
gastric cancer after surgery/enteral nutrition/tolerance分类
医药卫生引用本文复制引用
佟佳华,储爱琴,王家成,孙琳..胃癌术后患者肠内营养不耐受的相关因素分析[J].滨州医学院学报,2023,46(6):434-437,4.基金项目
国家临床重点专科建设项目(国卫办医涵[2018]292号) （国卫办医涵[2018]292号）
