川北医学院学报2023，Vol.38Issue(12)：1603-1607,5.DOI:10.3969/j.issn.1005-3697.2023.12.004
复方丹参滴丸联合氯吡格雷片对老年冠心病冠脉内介入术后心绞痛患者的治疗效果
Therapeutic effect of compound Danshen dripping pills combined with clo-pidogrel tablets on patients with angina pectoris after percutaneous coro-nary intervention for coronary heart disease
摘要
Abstract
Objective:To analyze the therapeutic effect of compound Danshen dripping pills combined with clopidogrel tablets on elderly patients with angina pectoris after percutaneous coronary intervention(PCI)for coronary heart disease.Methods:110 elderly patients with angina pectoris after PCI for coronary heart disease were selected and divided into control group(conventional treatment + clopidogrel tablets)and combined group(compound Danshen dripping pills on the basis of control group)according to the different treatment methods.The efficacy,angina pectoris attacks,myocardial enzymes,hemorheological indicators,vascular endothelial function indicators,LPa,ApoA1 and ApoB and occurrence of adverse reactions were compared between the two groups.Results:Compared with the control group,the combined group had a higher total effective rate,and lower frequency and duration of angina pectoris attacks.After treatment,levels of CK,LDH and CK-MB,BV high-shear,PV and BV low-shear,ET-1,LPa,and apoB in both groups decreased,and the combined group was lower than the control group(P<0.05).The levels of FMD,NO and apoA1 increased,and the combined group was higher than the control group(P<0.05).There were no significant differences in the adverse reactions between both groups(P>0.05).Conclusion:Compound Danshen dripping pills combined with clopidogrel tablets has a definite efficacy in the treatment of angina pectoris after PCI,and it can effectively relieve the symptoms of angina pectoris,improve the hemorheology,and regulate the vas-cular endothelium and lipid metabolism,and it has good safety and is worthy of application.关键词
复方丹参滴丸/氯吡格雷片/冠心病冠脉内介入术/心绞痛/心肌酶Key words
Compound Danshen dripping pills/Clopidogrel tablets/Percutaneous coronary intervention for coronary heart dis-ease/Angina pectoris/Myocardial enzymes分类
医药卫生引用本文复制引用
李劲松,田茂,刘晓楚,王斌,汪宇..复方丹参滴丸联合氯吡格雷片对老年冠心病冠脉内介入术后心绞痛患者的治疗效果[J].川北医学院学报,2023,38(12):1603-1607,5.基金项目
四川省科技创新苗子工程资助项目(2022099) （2022099）
