川北医学院学报2023，Vol.38Issue(12)：1651-1655,5.DOI:10.3969/j.issn.1005-3697.2023.12.015
腹泻灸联合艾针灸对乳腺癌患者术后恶心呕吐及血清胃肠激素和5-羟色胺水平的影响
Effects of diarrhea moxibustion combined with moxibustion on postopera-tive nausea and vomiting,serum gastrointestinal hormones and 5-HT levels in patients with breast cancer
摘要
Abstract
Objective:To investigate the effect of diarrhea moxibustion combined with moxibustion on postoperative nausea and vomiting(PONV)and serum gastrointestinal hormones and 5-HT levels in patients with breast cancer.Methods:124 patients with breast cancer who were selected to undergo radical mastectomy were selected as the research subjects,and they were divided into control group and observation group according to different antiemetic treatment methods,with 62 cases in each group.The patients in the control group were given conventional antiemetic treatment,and the patients in the observation group were given diarrhea moxibustion + moxa acupuncture 30 minutes before anesthesia.The incidence and severity of PONV at each time point(30 min,6,12 and 24 h after opera-tion),serum gastrointestinal hormones[serum gastrin(GAS),vasoactive intestinal peptide(VIP),motilin(MTL)]and 5-hydroxytryptamine(5-HT)before operation and 12 h after operation,the first exhaust and defecation time after operation,hospitalization time and hospitalization cost were compared between the two groups.Results:At 6,12 and 24 h after operation,the incidence of PONV in the observation group was lower than that in the control group(P<0.05),and the severity of PONV was better than that in the con-trol group(P<0.05).At12 h after operation,GAS and MTL in the two groups decreased,and the observation group was higher than the control group(P<0.05).At12 hours after operation,VIP and5-HT in both groups increased,and the observation group was lower than the control group(P<0.05).The first exhaust and defecation time and hospitalization time in the observation group were shorter than those in the control group(P<0.05),and the hospitalization cost was less than that in the control group(P<0.05).Conclu-sion:Diarrhea moxibustion combined with moxibustion has a significant effect on preventing PONV in breast cancer patients,and can regulate gastrointestinal hormones,reduce postoperative 5-HT levels,and promote patient recovery.关键词
乳腺癌根治术/腹泻灸/艾针灸/术后恶心呕吐/胃肠激素/5-羟色胺Key words
Radical mastectomy/Diarrhea moxibustion/Ai acupuncture/Postoperative nausea and vomiting/Gastrointestinal hormones/5-hydroxytryptamine分类
医药卫生引用本文复制引用
刘容,陈建米..腹泻灸联合艾针灸对乳腺癌患者术后恶心呕吐及血清胃肠激素和5-羟色胺水平的影响[J].川北医学院学报,2023,38(12):1651-1655,5.基金项目
广西壮族自治区中医药管理局自筹经费科研项目(GZZC2020309) （GZZC2020309）
