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基于高分辨质谱的食品致敏蛋白检测研究进展

刘楠 许利丽 张晓梅 宗爱珍 徐同成 尤艳莉 张鸿伟 肖晶

分析测试学报2023,Vol.42Issue(12):1666-1672,7.
分析测试学报2023,Vol.42Issue(12):1666-1672,7.DOI:10.19969/j.fxcsxb.23053003

基于高分辨质谱的食品致敏蛋白检测研究进展

Research Progress on Detection of Food Allergic Protein Based on High-resolution Mass Spectrometry

刘楠 1许利丽 2张晓梅 3宗爱珍 2徐同成 2尤艳莉 4张鸿伟 3肖晶5

作者信息

  • 1. 烟台大学 生命科学学院,山东 烟台 264000||山东省农业科学研究院农产品加工与营养研究所,山东 济南 250000
  • 2. 山东省农业科学研究院农产品加工与营养研究所,山东 济南 250000
  • 3. 青岛海关技术研究中心,山东 青岛 266100
  • 4. 烟台大学 生命科学学院,山东 烟台 264000
  • 5. 国家食品安全风险评估中心,北京 100022
  • 折叠

摘要

Abstract

Food allergen is tightly related to food safety,and technological progresses on the issue are realistically valuable to food allergy risk assessment.Compared with conventional immunological technique such as enzyme-linked immunosorbent assay(ELISA),high-resolution mass spectrometry(HRMS)is burgeoning in recent years for food allergic protein with its high-throughput characteriza-tion.In this paper,the research progress of HRMS technology for allergic protein detection is mainly reviewed,and extraction,purification and enzymatic hydrolysis of allergic protein,as well as HRMS-based analysis strategy and data acquisition is emphatically highlighted.Additionally,the challenges in the detection of allergic protein were also analyzed.

关键词

高分辨质谱/致敏蛋白/检测

Key words

high-resolution mass spectrometry/food allergic protein/detection

分类

化学化工

引用本文复制引用

刘楠,许利丽,张晓梅,宗爱珍,徐同成,尤艳莉,张鸿伟,肖晶..基于高分辨质谱的食品致敏蛋白检测研究进展[J].分析测试学报,2023,42(12):1666-1672,7.

基金项目

山东省重点研发计划(重大科技创新工程)项目(2021CXGC010807) (重大科技创新工程)

青岛海关科研项目(QK202101) (QK202101)

分析测试学报

OA北大核心CSCDCSTPCD

1004-4957

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