分析测试学报2023,Vol.42Issue(12):1666-1672,7.DOI:10.19969/j.fxcsxb.23053003
基于高分辨质谱的食品致敏蛋白检测研究进展
Research Progress on Detection of Food Allergic Protein Based on High-resolution Mass Spectrometry
摘要
Abstract
Food allergen is tightly related to food safety,and technological progresses on the issue are realistically valuable to food allergy risk assessment.Compared with conventional immunological technique such as enzyme-linked immunosorbent assay(ELISA),high-resolution mass spectrometry(HRMS)is burgeoning in recent years for food allergic protein with its high-throughput characteriza-tion.In this paper,the research progress of HRMS technology for allergic protein detection is mainly reviewed,and extraction,purification and enzymatic hydrolysis of allergic protein,as well as HRMS-based analysis strategy and data acquisition is emphatically highlighted.Additionally,the challenges in the detection of allergic protein were also analyzed.关键词
高分辨质谱/致敏蛋白/检测Key words
high-resolution mass spectrometry/food allergic protein/detection分类
化学化工引用本文复制引用
刘楠,许利丽,张晓梅,宗爱珍,徐同成,尤艳莉,张鸿伟,肖晶..基于高分辨质谱的食品致敏蛋白检测研究进展[J].分析测试学报,2023,42(12):1666-1672,7.基金项目
山东省重点研发计划(重大科技创新工程)项目(2021CXGC010807) (重大科技创新工程)
青岛海关科研项目(QK202101) (QK202101)