分子影像学杂志2023，Vol.46Issue(6)：1070-1075,6.DOI:10.12122/j.issn.1674-4500.2023.06.19
基于颅脑MRI灌注成像及临床指标构建缺血性脑梗死患者预后预测模型
A prognostic model for patients with ischemic cerebral infarction was established based on cerebral MRI perfusion imaging and clinical indicators
刘军平 1王安琴 1谷好好 1李良勇2
作者信息
- 1. 安徽中医药大学第一附属医院影像中心,安徽 合肥 230011
- 2. 安徽中医药大学第一附属医院脑血管介入科,安徽 合肥 230011
- 折叠
摘要
Abstract
Objective To investigate the risk factors of poor prognosis in patients with ischemic cerebral infarction,and construct a nomogram model of poor prognosis in patients with ischemic cerebral infarction based on cerebral MRI perfusion imaging and clinical indicators.Methods A total of 100 patients with ischemic cerebral infarction who came to our hospital from July 2021 to January 2023 were selected as the study objects,and cerebral MRI perfusion imaging was performed on the patients.According to the prognosis,patients were divided into poor prognosis group(n=47)and good prognosis group(n=53).Logistic regression analysis was used to screen the risk factors of poor prognosis in patients with ischemic cerebral infarction.R4.2.0 software was used to establish and verify the poor prognosis of patients with ischemic cerebral infarction.Results Logistic regression analysis showed that age≥60 years old,NIHSS score>12 points at admission,major infarction,posterior circulation cerebral infarction,affected time to peak and affected mean transit time were risk factors for poor prognosis in patients with ischemic cerebral infarction,and affected cerebral blood volume and affected cerebral blood flow were protective factors for poor prognosis in patients with ischemic cerebral infarction(P<0.05).The results of the constructed nomogram model for poor prognosis of patients with ischemic cerebral infarction showed that the actual value of the correction curve was in good agreement with the predicted value,the area under ROC curve of the model was 0.778(95%CI:0.735-0.821).When the decision curve showed that the threshold probability was 1%-100%,the net benefit value of the histogram predicting the poor prognosis of patients with ischemic cerebral infarction was higher.Conclusion The nomogram model of poor prognosis of patients with ischemic cerebral infarction based on cerebral MRI perfusion imaging and clinical indicators has high accuracy and clinical application value,and can be used to predict poor prognosis of patients with ischemic cerebral infarction.关键词
磁共振成像/灌注成像/缺血性脑梗死/预后/列线图Key words
magnetic resonance imaging/perfusion imaging/ischemic cerebral infarction/prognosis/column diagram引用本文复制引用
刘军平,王安琴,谷好好,李良勇..基于颅脑MRI灌注成像及临床指标构建缺血性脑梗死患者预后预测模型[J].分子影像学杂志,2023,46(6):1070-1075,6.
