广西医学2023，Vol.45Issue(19)：2315-2320,6.DOI:10.11675/j.issn.0253-4304.2023.19.04
CT引导下肺结节定位针拖尾法定位联合胸腔镜肺段切除术治疗早期肺腺癌的临床效果
Clinical effect of CT-guided localization of pulmonary nodule with locating needle and trailing technique combined with thoracoscopic pulmonary segmentectomy for the treatment of pulmonary adenocarcinoma in early stage
摘要
Abstract
Objective To investigate the clinical effect of CT-guided localization of pulmonary nodule with locating needle and trailing technique combined with thoracoscopic pulmonary segmentectomy for the treatment of pulmonary adenocarcinoma in early stage.Methods A total of 110 patients with pulmonary adenocarcinoma in early stage were selected,and they were randomly divided into observation group(n =57)or control group(n =53).The observation group was treated with CT-guided localization of pulmonary nodule with locating needle and trailing technique combined with thoracoscopic pulmonary segementectomy,while the control group received routine CT-guided localization combined with thoracoscopic pulmonary segmentectomy for treatment.The operative indices,and pre-and postoperative pulmonary function indices,tumor markers,survival quality,as well as the incidence rate of operative complications were compared between the two groups.Results The localization time,drainage time,and postoperative length of hospital stay in the observation group were shorter than those in the control group,and the accuracy rate of one-time localization was higher than that in the control group(P<0.05);however,no statistically significant difference in operation duration,intraoperative bleeding volume,drainage volume,and number of lymph node dissection was found between the two groups(P>0.05).After 3 months of operation,the maximum voluntary ventilation,forced expiratory volume in one second,forced vital capacity,and diffusion lung capacity for carbon monoxide in the two groups were decreased as compared with before operation,but the observation group exhibited superior aforementioned pulmonary function indices to compared with the control group(P<0.05).The scores of quality of survival in various fields and total score in the two groups were elevated as compared with before operation(P<0.05),but there was no statistically significant difference in the scores of quality of survival in various fields and total score between the two groups(P>0.05).There was no statistically significant difference in pre-and postoperative serum carcinoembryonic antigen,carbohydrate antigen 125,cytokeratin 19 fragment antigen 21-1,and squamous cell carcinoma antigen levels between the two groups,and no statistically significant difference in the incidence rate of operative complications was found between the two groups(P>0.05).Conclusion When undergoing thoracoscopic pulmonary segmentectomy for the treatment of pulmonary adenocarcinoma in early stage,employing CT-guided localization of pulmonary nodule with locating needle and trailing technique is helpful for preoperative accurate localization of lesions,shortening intraoperative localization time and drainage time,which has less effect on patients′pulmonary function,and promotes patients′postoperative recovery.关键词
肺腺癌/早期/CT/肺结节定位针拖尾法/胸腔镜肺段切除术/定位方法Key words
Pulmonary adenocarcinoma/Early stage/CT/Localization of pulmonary nodule with locating needle and trailing technique/Thoracoscopic pulmonary segmentectomy/Localization method分类
医药卫生引用本文复制引用
辛兴,李凤卫,陈应泰,边建伟,刘思杰,吴迅..CT引导下肺结节定位针拖尾法定位联合胸腔镜肺段切除术治疗早期肺腺癌的临床效果[J].广西医学,2023,45(19):2315-2320,6.基金项目
北京市科技计划课题(Z201100005520071) （Z201100005520071）
