海南师范大学学报（自然科学版）2023，Vol.36Issue(4)：415-419,5.DOI:10.12051/j.issn.1674-4942.2023.04.009
薜荔叶化学成分及其活性研究
Studies on Chemical Constituents and Activities from Leaves of Ficus pumila
摘要
Abstract
Seven compounds have been isolated from 80%ethanol extract of F.Pumila leaves by silica gel,ODS column chromatographies,Sephadex LH-20,and semi-preparative HPLC.Their structures were determined by physicochemical properties and spectral data analyses,and compared with literature data.The compounds were identified as 3-hydroxy-damascone(1),ethyl laurate(2),coriolic acid(3),13-hydroxy-(9Z,11E,15E)-octadecatrienoic acid(4),ethyl-β-D-gluco-pyranoside(5),benzyl-β-D-glucopyranoside(6)and 2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-propane-1,3-diol(7).Compound 7 was isolated from the genus of Ficus for the first time,and coumpound 1 was isolated from F.Pumila for the first time.Compound 1 displayed the cytotoxicity against A549 cells with IC50 value of 32.21 μg/mL.All compounds exhibited no antibacterial activity against the four human pathogenic bacterium and two vibrios.关键词
薜荔/化学成分/抗肿瘤活性/抗菌活性Key words
Ficus pumila/chemical constituents/antitumor activity/antibacterial activity分类
医药卫生引用本文复制引用
蔡月,赖宣丞,石慧,王越,韩长日..薜荔叶化学成分及其活性研究[J].海南师范大学学报（自然科学版）,2023,36(4):415-419,5.基金项目
国家自然科学基金项目(81360478,21362009) （81360478,21362009）
