河北医学2023，Vol.29Issue(12)：2049-2054,6.DOI:10.3969/j.issn.1006-6233.2023.12.021
载药微球经动脉化疗栓塞对比碘油栓塞治疗中晚期肝癌的有效性及安全性分析
Effectiveness and Safety Analysis of Drug-Eluting Microsphere Transarterial Chemoembolization Compared with Conventional Transarterial Chemoembolization in the Treatment of Intermediate to Advanced Hepatocellular Carcinoma
摘要
Abstract
Objective:To analyze the application value of drug-eluting microsphere transarterial chemo-embolization(DEB-TACE)compared with conventional transarterial chemoembolization(cTACE)in inter-mediate to advanced hepatocellular carcinoma.Methods:A retrospective analysis was conducted on patients with intermediate to advanced hepatocellular carcinoma in our hospital from March 2018 to March 2021.The patients were grouped according to the treatment method,with 92 cases undergoing DEB-TACE(included in the DEB-TACE group)and 125 cases undergoing cTACE(included in the cTACE group).The efficacy and safety of the two groups were compared.Results:The disease remission rate in the DEB-TACE group was higher than that in the cTACE group at 1 month after surgery.The differences in TBIL,ALT,AST,and AFP before and after surgery were greater in the DEB-TACE group than in the cTACE group.The severity of post-operative vomiting was lower in the DEB-TACE group than in the cTACE group.The one-year survival rate was higher in the DEB-TACE group than in the cTACE group(P<0.05).Conclusion:DEB-TACE treat-ment is more effective for intermediate to advanced hepatocellular carcinoma,with fewer complications and higher safety.关键词
载药微球经动脉化疗栓塞术/经动脉化疗栓塞术/肝癌/中晚期Key words
Drug-eluting beads transarterial chemoembolization/Transcatheter arterial chemoem-bolization/Liver cancer/Middle-to-advanced stage引用本文复制引用
梁黎,丁文彬,徐管梅,钱静,江晓冬,王玲玲..载药微球经动脉化疗栓塞对比碘油栓塞治疗中晚期肝癌的有效性及安全性分析[J].河北医学,2023,29(12):2049-2054,6.基金项目
江苏省2020年省基础研究计划自然科学基金项目,(编号:BK20200192) （编号:BK20200192）
中国健康促进基金会"肿瘤介入科研基金",(编号:XM_2018_011_0006_01) （编号:XM_2018_011_0006_01）
