中国实用神经疾病杂志2024，Vol.27Issue(1)：37-42,6.DOI:10.12083/SYSJ.230708
全脑CT灌注及磁共振弥散加权成像评价短暂性脑缺血发作继发脑梗死的价值
Evaluative value of whole brain CT perfusion and magnetic resonance diffusion weighted imaging for secondary cerebral infarction following transient ischemic attack
摘要
Abstract
Objective To probe the evaluative value of whole brain CT perfusion and magnetic resonance diffusion weighted imaging(DWI)for transient ischemic attack(TIA)secondary cerebral infarction.Methods A retrospective analysis was conducted on the clinical data of 70 patients with TIA admitted to the 902nd Hospital of China People's Liberation Army Joint Logistic Support Force from June 2022 to April 2023.Based on the clinical diagnosis of secondary cerebral infarction within 7 days after the onset of the disease,the patients were divided into cerebral infarction group(n=22)and non-cerebral infarction group(n=48).The differences in CT perfusion parameters between the two groups were compared,and the optimal threshold for diagnosing TIA secondary cerebral infarction was determined through ROC curve analysis and combined data analysis,the sensitivity and specificity of whole brain CT perfusion parameters,DWI,and two combined diagnostic methods for TIA secondary cerebral infarction were compared,and their consistency through Kappa values were analyzed.Results The CBF and CBV in the cerebral infarction group were lower than those in the non-cerebral infarction group,while TTP and MTT were higher than those in the non-cerebral infarction group(P<0.05).The AUC of TIA secondary cerebral infarction diagnosed with CBF,CBV,TTP,and MTT using ROC analysis was 0.670,0.854,0.681,and 0.754,respectively.The AUC of TIA secondary cerebral infarction diagnosed with combined data was 0.925.Using clinical diagnosis as the gold standard,the sensitivity of whole brain CT perfusion in diagnosing TIA secondary cerebral infarction is 77.27%,the specificity is 95.83%,and the Kappa value is 0.759.The sensitivity,specificity,and Kappa value of magnetic resonance diffusion weighted imaging in diagnosing TIA secondary cerebral infarction were 81.82%,97.92%,and 0.828,respectively.The sensitivity and specificity of the two combined diagnoses for TIA secondary cerebral infarction were 95.45%,95.83%,and the Kappa value was 0.902,indicating a good consistency.Conclusion Both whole brain CT perfusion and DWI have certain value in diagnosing TIA secondary cerebral infarction,and the combined diagnosis accuracy of the two is better.关键词
短暂性脑缺血发作/脑梗死/全脑CT灌注/磁共振弥散加权成像/预测价值Key words
Transient ischemic attack/Cerebral infarction/Whole brain CT perfusion/Magnetic resonance diffusion weighted imaging/Predictive value分类
医药卫生引用本文复制引用
常小娜,卢睿,杨世泉,何文进,蔡炜琼,钟立清,丁庆社,代琳玉,郑美娴,邱广美,曹玉竹..全脑CT灌注及磁共振弥散加权成像评价短暂性脑缺血发作继发脑梗死的价值[J].中国实用神经疾病杂志,2024,27(1):37-42,6.基金项目
联勤保障部队战勤部面上重点项目(编号:CLB20J026) （编号:CLB20J026）
