中国实用神经疾病杂志2024,Vol.27Issue(1):113-118,6.DOI:10.12083/SYSJ.230883
长链非编码RNA H19在中枢神经系统疾病中的研究进展
Research progress of long non-coding RNA H19 in central nervous system diseases
摘要
Abstract
Statistics show that the incidence of central nervous system diseases is increasing year by year.Central nervous system diseases seriously endanger human life and health with extremely high mortality and disability rates.At the same time,its pathogenesis is still lack of effective research,and has become one of the hot issues of current research.LncRNA H19 was originally considered as"transcriptional noise"and is now widely proved to be related to the pathogenesis and progression of various central nervous system diseases,This article summarizes the function and mechanism of LncRNA H19 in a variety of central nervous system diseases,such as neurodegenerative diseases,cerebrovascular diseases,intracranial tumors,spinal cord injury and epilepsy,and provides a theoretical basis for further study of the role of LncRNA H19 in nervous system diseases.关键词
LncRNA H19/长链非编码RNA/中枢神经系统疾病/神经退行性病变/脑血管疾病/颅内肿瘤/脊髓损伤/癫痫/作用机制Key words
LncRNA H19/Long non-coding RNA/Central nervous system diseases/Neurodegenerative diseases/Cerebrovascular diseases/Intracranial tumors/Spinal cord injury/Epilepsy/Mechanism of action分类
医药卫生引用本文复制引用
田烨楠,吕鹤群,冯瑶婷,彭拥军..长链非编码RNA H19在中枢神经系统疾病中的研究进展[J].中国实用神经疾病杂志,2024,27(1):113-118,6.基金项目
国家自然科学基金面上项目(编号:82174484,81973932) (编号:82174484,81973932)
江苏省中医院高峰学术人才项目(编号:k2021rc24) (编号:k2021rc24)
江苏省第六期"333高层次人才培养工程" ()
江苏省中医院专项课题(编号:Y2022ZR20) (编号:Y2022ZR20)