基于网络药理学和分子对接探讨桂枝汤治疗动脉粥样硬化的作用机制OA
Study on the Action Mechanism of Cinnamon Twig Decoction in the Treatment of Atherosclerosis Based on Network Pharmacology and Molecular Docking
目的:运用网络药理学和分子对接研究桂枝汤治疗动脉粥样硬化(atherosclerosis,AS)的分子机制.方法:通过中药系统药理学数据库与分析平台(traditional Chinese medicine systems pharmacology database and analysis platform,TCMSP)获取桂枝汤组方中药的活性成分及相关靶点,通过Cytoscape 3.9.1构建"桂枝汤-活性成分-作用靶点"网络并进行拓扑分析…查看全部>>
Objective:To study the molecular mechanism of Cinnamon Twig Decoction in the treatment of atherosclerosis(AS)by using network pharmacology and molecular docking.Methods:The active ingredients and related targets of Cinnamon Twig Decoction were ob-tained through the traditional Chinese medicine systems pharmacology database and analysis platform(TCMSP),and the"Cinnamon Twig Decoction-active ingredients-targets"network was constructed by Cytoscape3.9.1 and the…查看全部>>
房慧琴;王佳宁;刘永吉;刘泳;赵军绩;臧运华
山东中医药大学,山东济南 250014青岛大学附属青岛市海慈医院,青岛市中医医院,山东青岛 266033青岛大学附属青岛市海慈医院,青岛市中医医院,山东青岛 266033青岛大学附属青岛市海慈医院,青岛市中医医院,山东青岛 266033青岛大学附属青岛市海慈医院,青岛市中医医院,山东青岛 266033青岛大学附属青岛市海慈医院,青岛市中医医院,山东青岛 266033
中医学
桂枝汤动脉粥样硬化网络药理学分子对接调和营卫《伤寒论》张仲景
Cinnamon Twig Decoctionatherosclerosis(AS)network pharmacologymolecular dockingregulating nutrient and defense qiTreatise on Cold Damage DiseasesZhang Zhongjing
《河南中医》 2023 (12)
1790-1799,10
山东省中医药科技发展计划项目(20190605)青岛市医药科研指导计划项目(2020WJZD226)
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