河南中医2023，Vol.43Issue(12)：1878-1883,6.DOI:10.16367/j.issn.1003-5028.2023.12.0360
排气饮联合加速康复外科对结直肠癌术后胃肠功能恢复的影响
The Influence of Wind-Breaking Beverage Combined with Enhanced Recovery After Surgery on Gastrointestinal Function Recovery After Colorectal Cancer
摘要
Abstract
Objective:To observe the influence of Wind-Breaking Beverage combined with enhanced recovery after surgery(ERAS)on gastrointestinal function after colorectal cancer.Methods:A total of 120 patients with colorectal cancer undergoing laparoscopic surgery were selected from the Department of General Surgery of Jiangsu Province Hospital of Chinese Medicine,and were divided into the con-trol group,the ERAS group and the Wind-Breaking Beverage+ERAS group according to the random number table method,with 40 ca-ses in each group.The control group was given conventional treatment during the perioperative period,the ERAS group was given clini-cal pathway intervention based on the concept of ERAS,and the Wind-Breaking Beverage+ERAS group was given Wind-Breaking Bev-erage for oral administration on the first day after surgery on the basis of the ERAS group.The first exhaust time,defecation time,first bowel sound recovery time,bowel sound rate within 3 days after surgery and the incidence of intestinal dysfunction in the three groups were observed,and the serum white blood cell count(WBC),C reactive protein(CPR),interleukin-6(IL-6)and visual analogue scale(VAS)scores before and after surgery in the three groups were compared.Results:The first exhaust time,first defecation time,bowel sound recovery time and bowel sound rate on the third day after surgery in the ERAS group and the Wind-Breaking Beverage+ERAS group were less than those in the control group,and each time of the Wind-Breaking Beverage+ERAS group was less than that of the ERAS group,with statistically significant differences(P＜0.05).The gastrin levels in the ERAS group and the Wind-Breaking Bever-age+ERAS group on the 1st and 3rd day after operation were higher than those in the control group,and the gastrin level in the Wind-Breaking Beverage+ERAS group was higher than that in the ERAS group,with statistically significant differences(P＜0.05).The lev-els of WBC,CRP and IL-6 in the ERAS group and the Wind-Breaking Beverage+ERAS group on the 3rd day after operation were lower than those in the control group and the 1st day before operation,and the levels of WBC,CRP and IL-6 in the Wind-Breaking Beverage+ERAS group were lower than those in the ERAS group,with statistically significant differences(P＜0.05).There was no difference in the VAS pain score on the 1st day after operation,and the VAS scores in the ERAS group and the Wind-Breaking Beverage+ERAS group on the 3rd day after operation were lower than those in the control group,and the VAS score in the Wind-Breaking Beverage+ERAS group was lower than that in the ERAS group,with statistically significant differences(P＜0.05).There were no statistically sig-nificant differences in the incidence of postoperative unplanned rehospitalization rate,anastomotic leakage,abdominal infection,intesti-nal obstruction,nausea and vomiting,diarrhea and other intestinal dysfunction among the three groups(P＞0.05).Conclusion:Wind-Breaking Beverage combined with ERAS can promote the recovery of gastrointestinal function after colorectal cancer surgery,and its mechanism may be related to controlling intestinal inflammation,reducing postoperative pain and increasing gastrin.关键词
结直肠癌术后/加速康复外科/排气饮/胃肠功能Key words
colorectal cancer/enhanced recovery after surgery(ERAS)/Wind-Breaking Beverage/gastrointestinal function分类
医药卫生引用本文复制引用
张传灼,孟达理..排气饮联合加速康复外科对结直肠癌术后胃肠功能恢复的影响[J].河南中医,2023,43(12):1878-1883,6.基金项目
江苏省中医院科技项目(Y20009) （Y20009）
