四川大学学报（医学版）2023，Vol.54Issue(6)：1250-1255,6.DOI:10.12182/20231160603
15例颅内泡型棘球蚴病的临床特点及手术疗效分析
Clinical Features and Surgical Outcomes of 15 Cases of Intracranial Alveolar Echinococcosis
摘要
Abstract
Objective To investigate the surgical treatment strategy of intracranial alveolar echinococcosis(AE)and the clinical outcomes.Methods The clinical and follow-up data of 15 intracranial AE patients who underwent surgical treatment in the Departments of Neurosurgery of Sichuan Provincial People's Hospital(SPPH)and People's Hospital of Aba Tibetan and Qiang Autonomous Prefecture(a branch hospital of SPPH)between March 2017 and January 2021 were retrospectively analyzed.Full follow-up data were available for each of the 15 cases.The clinical and imaging characteristics,general surgical information,and surgical outcomes were analyzed.Results In the 15 patients,there were a total of 50 intracranial lesions,with an average of(3.3±3.1)/case.Four cases had solitary intracranial lesions,while 11 cases had multiple lesions,with the number of intracranial lesions per case ranging from 2 to 13.All patients with solitary intracranial lesions received total resection.In 6 patients with multiple intracranial lesions,only the largest lesion was surgically removed,and in 5 patients,2 to 3 adjacent lesions were surgically removed.All but one patient had extracranial lesions in their liver,lungs,kidneys,adrenal glands,and thoracic vertebrae.The patients were followed up for 12 to 58 months after surgery,with the mean follow-up time being(28.1±13.4)months.Among the 15 cases,13 showed stable intracranial condition during postoperative follow-up.Intracranial lesions recurred in 2 patients who had deep lesions accompanied by dissemination to the subarachnoid space.Two patients died during follow-up.Conclusion Microsurgical treatment of intracranial AE is effective,but total surgical resection is difficult to accomplish when patients have echinococcosis lesions located at a depth,especially when the lesions are spreading to the subarachnoid space.The prognosis of patients is closely associated with the extent of lesion invasion and the control of systemic hydatid lesions,especially those in the liver.关键词
颅内/泡型棘球蚴病/外科手术/阿苯达唑Key words
Intracranial/Alveolar echinococcosis/Surgery/Albendazole引用本文复制引用
文家智,刘进平,王奇,费帆,廖晓灵,陈勇,袁莉,陈增雄,陈隆益,徐如祥..15例颅内泡型棘球蚴病的临床特点及手术疗效分析[J].四川大学学报（医学版）,2023,54(6):1250-1255,6.基金项目
阿坝州科技局重点研发项目(No.20YYJSYJ0016)资助 （No.20YYJSYJ0016）
