海洋科学2023，Vol.47Issue(10)：87-93,7.DOI:10.11759/hykx20220120004
两种不同海洋生物材料对大鼠急性创面修复效果的研究
Effect of two different marine biomaterials on acute wound repair in rats
摘要
Abstract
To investigate the wound healing effects of marine fish collagen and alginate,we established rat skin acute wound models and evaluated the efficacy of these two materials.We employed commonly used clinical wound dressing methods by implanting both materials into the wounds and observed and evaluated the outcomes using cell biology and pathology techniques.The results indicated that both fish collagen and alginate exhibited excellent biocompatibility and the ability to stimulate wound repair.However,fish collagen outperformed alginate in terms of promoting blood vessel ingrowth,material degradation and fusion,and overall wound healing.These findings demonstrate that both marine biomaterials create a conducive environment for wound healing and effec-tively facilitate the wound repair process.关键词
创面修复/海藻酸盐/胶原蛋白/诱导Key words
wound repair/alginate/collagen/induction分类
生物科学引用本文复制引用
王蕾,吕康宁,李文军,王凯,姜晓锐,秦松..两种不同海洋生物材料对大鼠急性创面修复效果的研究[J].海洋科学,2023,47(10):87-93,7.基金项目
山东省重点研发计划(重大科技创新工程)(2019JZZY011103)Shandong Province Key Research and Development Plan(Major Scientific and Technological Innovation Project),No.Project 2019JZZY011103 （重大科技创新工程）
