实用心电学杂志2023，Vol.32Issue(6)：405-410,6.DOI:10.13308/j.issn.2095-9354.2023.06.005
肥厚型心肌病患者合并心房颤动的危险因素及预后分析
Risk factors and prognosis analysis of patients with hypertrophic cardiomyopathy complicating atrial fibrillation
摘要
Abstract
Objective To investigate the clinical characteristics,risk factors and prognosis of patients with hypertrophic cardiomyopathy(HCM)accompanied with atrial fibrillation(AF).Methods Outpatients or inpatients with HCM were selected,and divided into AF group and non-AF group based on the presence or absence of AF.The clinical features and prognosis of the two groups were observed.Multiple Logistic regression analysis was applied in exploring the risk factors of HCM patients complicating AF.Results A total of 144 HCM patients are enrolled in our study,with 32 patients(22.2%)in the AF group and 112 patients(77.8%)in the non-AF group.Multiple Logistic regression analysis reveals that enlarged left atrial diameter(LAD,OR=2.013,P=0.004)and reduced left ventricular ejection fraction(LVEF,OR= 0.920,P＜0.01)are independent risk factors for HCM patients with AF.During an average follow-up period of two years and three months,the readmission rate of patients in the AF group is significantly higher than that in the non-AF group(P＜0.05);there is no significant difference in the primary endpoints(death)or other secondary endpoints(heart failure and thrombembolia)between the two groups(P＞0.05).Conclusion The readmission rate of HCM patients complicated by AF is significantly increased.The enlarged LAD and reduced LVEF are independent risk factors for complicated AF among HCM patients.关键词
肥厚型心肌病/心房颤动/危险因素/预后Key words
hypertrophic cardiomyopathy/atrial fibrillation/risk factor/prognosis分类
医药卫生引用本文复制引用
曹丹宁,周碧蓉..肥厚型心肌病患者合并心房颤动的危险因素及预后分析[J].实用心电学杂志,2023,32(6):405-410,6.基金项目
安徽省学术技术带头人科研项目(2021D279) （2021D279）
