江西科学2023，Vol.41Issue(6)：1048-1049,1070,3.DOI:10.13990/j.issn1001-3679.2023.06.003
补肾清热合剂治疗外周性性早熟女童的临床疗效与评价
Clinical Effect and Evaluation of Bushen Qingre Mixture in Treating Children with Peripheral Precocious Puberty
摘要
Abstract
Objective:To explore the clinical efficacy and safety of Bushen Qingre mixture in the treatment of children with peripheral precocious puberty.Methods:A total of 40 children with pe-ripheral precocious puberty in our hospital were selected and treated with Bushen Qingre mixture.The height,weight,uterine volume,ovarian volume,estrogen levels,breast stage and adverse e-vents were observed.Results:The height of children gradually increased after 3 and 6 months of treatment with Bushen Qingre mixture,but some children did not increase at 9 months,and contin-ued to increase at 12 months.After 3 to 6 months of treatment,the weight increased slowly.After 3 to 12 months of treatment,uterine volume and ovarian volume increased slowly.The level of estradi-ol decreased rapidly after 3 months of treatment,but increased again after 6 to 12 months of treat-ment in some children.After treatment with Bushen Qingre mixture,the breast stage of the child re-mained unchanged at B2-B3.All children had no adverse reactions during oral administration of Bushen Qingre mixture.Conclusion:Bushen Qingre mixture is effective in the treatment of children with peripheral precocious puberty,and has less adverse reactions.It is worthy of application.关键词
补肾清热合剂/外周性性早熟/雌激素Key words
Bushen Qingre mixture/peripheral precocious puberty/estrogen分类
医药卫生引用本文复制引用
熊友健,陶艳红,张东光,胡榕..补肾清热合剂治疗外周性性早熟女童的临床疗效与评价[J].江西科学,2023,41(6):1048-1049,1070,3.基金项目
江西省中医药管理局科技计划项目(2021B611). （2021B611）
