摘要
Abstract
Objective:To analyze the incidence and influencing factors of vascular pedicle ossification after the repair of maxillofacial defects by free flap.Methods:Search PubMed,Web of Science and CNKI databases for keywords"pedicle ossification","free flap"and"maxillofacial".The literatures on heterotopic ossification of free flap vascular pedicle from January 1,2000 to December 1,2021 were obtained.RevMan 5.4 software was used for meta analysis.Results:Five literatures were included,consisting of 829 cases in total.The incidence of heterotopic ossification of vascular pedicle visible on imaging examinations was about 11%,and the incidence of ossification with clinical symptoms was about 2%.The combined odds ratio showed that the occurrence of heterotopic ossification of vascular pedicle was significantly correlated with flap type(OR=14.01,95%CI=3.58-54.85,P<0.001),but not with gender(OR=1.63,95%CI=1.00-2.67,P=0.05),site of reconstruction(OR=0.90,95%CI=0.46-1.74,P>0.05),or whether radiotherapy had been performed(OR=0.79,95%CI=0.52-1.22,P>0.05).Conclusion:After the repair of maxillofacial defects by free flap,the incidence of heterotopic ossification of vascular pedicle visible on imaging examinations was about 11%,and the incidence of ossification with clinical symptoms was about 2%,which was mainly related to the type of free flap and mostly occurred in free fibular flap.关键词
游离皮瓣/腓骨瓣/血管蒂骨化/修复重建/颌骨缺损Key words
free flap/fibula flap/vascular pedicle ossification/repair and reconstruction/jaw bone defect分类
医药卫生
