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Ghrelin基因多态性对癌症的影响

吴威 侯启亮 王森 袁子茜 高兴梅 周洁容 李斌

兰州大学学报(医学版)2023,Vol.49Issue(10):73-79,88,8.
兰州大学学报(医学版)2023,Vol.49Issue(10):73-79,88,8.DOI:10.13885/j.issn.1000-2812.2023.10.010

Ghrelin基因多态性对癌症的影响

The Influence of Ghrelin Gene Polymorphism on Cancer

吴威 1侯启亮 1王森 1袁子茜 1高兴梅 1周洁容 1李斌2

作者信息

  • 1. 兰州大学 第一临床医学院,甘肃 兰州 730000
  • 2. 兰州大学 第一临床医学院,甘肃 兰州 730000||兰州大学第一医院 重症医学科,甘肃 兰州 730000
  • 折叠

摘要

Abstract

Ghrelin initially garnered attention for its role in regulating growth hormone secretion and appetite.Recent studies have unveiled its significant role in various cancers.This review explored the potential associa-tion between ghrelin gene polymorphisms and a range of cancers,including non-Hodgkin lymphoma,colorec-tal,liver and breast cancer.Additionally,we emphasized the multifaceted role of ghrelin in various biological processes relevant to cancer,including obesity,apoptosis,inflammation,immunity,stem cell differentiation and angiogenesis.While the precise mechanisms by which ghrelin impacts the field of cancer require further research,this area of study was poised to offer novel perspectives and strategies for cancer prevention and treatment.

关键词

ghrelin/基因多态性/非霍奇金淋巴瘤/结直肠癌/肝癌/乳腺癌

Key words

ghrelin/gene polymorphism/non-Hodgkin lymphoma/colorectal cancer/liver cancer/breast cancer

分类

医药卫生

引用本文复制引用

吴威,侯启亮,王森,袁子茜,高兴梅,周洁容,李斌..Ghrelin基因多态性对癌症的影响[J].兰州大学学报(医学版),2023,49(10):73-79,88,8.

基金项目

国家自然科学基金资助项目(82160358) (82160358)

兰州大学学报(医学版)

OACSTPCD

2097-681X

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