临床神经外科杂志2023，Vol.20Issue(6)：601-606,613,7.DOI:10.3969/j.issn.1672-7770.2023.06.001
脑结构位移对脑深部电刺激电极移位的影响
Influence of brain shift on lead displacement during deep brain stimulation
摘要
Abstract
Objective To explore the effect of brain shift on electrode displacement during deep brain stimulation(DBS)and its related factors.Methods A total of 268 patients who underwent bilateral subthalamic nucleus(STN)DBS and 31 patients who underwent bilateral internal globus pallidus(GPi)DBS,admitted to Beijing Tiantan Hospital from October 2018 to June 2021,were involved in this study.The lead localization was based on preoperative magnetic resonance imaging(MRI),immediate postoperative and longer follow-up computed tomography(CT).Unilateral pneumocephalus volume percent(uPVP)and brain volume percent were also evaluated.Results Advanced normalization tools(ANTs)followed by brain shift correction performed efficiently.After minimizing brain shift during STN-DBS,lead position immediately postoperation was(0.29± 0.47)mm medial and(0.63±0.55)mm posterior.Slightly different results were obtained in GPi-DBS(0.21±0.66)mm medial,(0.96±0.53)mm posterior,and(0.17±0.67)mm ventral.The uPVP was significantly related to lead displacement.Conclusion The lead position immediately post-operation is medially,posteriorly and ventrally displaced,and is related to uPVP.关键词
脑深部电刺激/电极移位/脑结构位移/气颅Key words
deep brain stimulation/lead displacement/brain shift/pneumocephalus分类
医药卫生引用本文复制引用
杜婷婷,陈颍川,袁天朔,朱冠宇,马若宇,张鑫,张建国..脑结构位移对脑深部电刺激电极移位的影响[J].临床神经外科杂志,2023,20(6):601-606,613,7.基金项目
国家自然科学基金资助项目(82101514) （82101514）
中国博士后科学基金面上资助项目(2022M722233) （2022M722233）
