临床神经外科杂志2023，Vol.20Issue(6)：630-635,6.DOI:10.3969/j.issn.1672-7770.2023.06.006
动脉瘤性蛛网膜下腔出血患者急性肺损伤的危险因素及其对预后的影响
Acute lung injury in patients with subarachnoid hemorrhage:risk factors,and impact on prognosis
摘要
Abstract
Objective To study the incidence of acute lung injury or acute respiratory distress syndrome(ALI/ARDS)in patients with subarachnoid hemorrhage(SAH)and to investigate the risk factors for ALI/ARDS occurrence and its impact on patient prognosis.Methods The clinical data of 167 consecutive patients with SAH admitted to the First Hospital of Soochow University from Jan 2018 to Dec 2021 were analyzed retrospectively.Multivariate logistic regression model was used to analyze the risk factors that influence the occurrence of ALI/ARDS and contribute to the poor prognosis of patients.Results Of the 167 patients,45 developed ALI/ARDS and 49 had a poor prognosis.In multivariate logistic regression analysis,elderly patients,lower glasgow coma scale(GCS),higher Hunt-Hess grade,higher simplified acute physiology score(SAPS)Ⅱ,gastric aspiration,hypoxemia,and tachypnea were associated with an increased incidence of ALI/ARDS.Meanwhile high Fisher's classification,low GCS score,higher Hunt-Hess grade,duration of mechanical ventilation,and ALI/ARDS were risk factors for poor prognosis.Conclusions Development of ALI/ARDS is a common complication in patients with SAH and is independently associated with poor neurological prognosis.Elderly patients,lower GCS,higher Hunt-Hess grade,higher SAPS Ⅱ score,aspiration,hypoxemia,and tachypnea were risk factors for ALI/ARDS.关键词
急性肺损伤/急性呼吸窘迫综合征/动脉瘤性蛛网膜下腔出血/危险因素/预后Key words
acute lung injury/acute respiratory distress syndrome/aneurysmal subarachnoid hemorrhage/risk factors/prognosis分类
医药卫生引用本文复制引用
高薇,张洪荣..动脉瘤性蛛网膜下腔出血患者急性肺损伤的危险因素及其对预后的影响[J].临床神经外科杂志,2023,20(6):630-635,6.基金项目
苏州市科技发展计划(医疗卫生科技创新-应用基础研究)项目(SKJYD2021079) （医疗卫生科技创新-应用基础研究）
