临床神经外科杂志2023，Vol.20Issue(6)：696-700,5.DOI:10.3969/j.issn.1672-7770.2023.06.018
应用内囊局部脑血流量规范化评估老年少量基底核出血手术指征的临床研究
Clinical study on application of regional cerebral blood flow normalization in the internal capsule to evaluate surgical indication of small basal ganglia hemorrhage in elderly
摘要
Abstract
Objective To evaluate the application value of regional cerebral blood flow(rCBF)in evaluating whether a small amount(15-30 mL)of hypertensive basal ganglia hemorrhage in the elderly has surgical indications.Methods The clinical data of 183 elderly patients with minor basal ganglia hemorrhage admitted to Xingtai Third Hospital from May 2019 to May 2022 were analyzed retrospectively.Based on the rCBF value measured by computer tomography perfusion(CTP)at the time of admission,they were divided into the mild insufficient perfusion group[rCBF≥15 mL/(100 g·min)]and the severe insufficient perfusion group[rCBF＜15 mL/(100 g· min)].In the two groups,according to whether the patients were operated or not,they were divided into the operation subgroup and the conservative subgroup.The difference of treatment effect between the two groups and the difference of rCBF in the internal capsule area before and after operation were compared.The application value of rCBF in deciding the surgical indication of elderly patients with small basal ganglia cerebral hemorrhage was evaluated.Results Compared with the conservative subgroup,the operative subgroup in the mild hypoperfusion group had no significant difference in treatment effectiveness,good prognosis and postoperative rCBF in the internal capsule area(P＞0.05).Compared with the conservative subgroup,the operative subgroup in the severe hypoperfusion group had significant difference in treatment effectiveness,good prognosis and postoperative rCBF in the internal capsule area(P＜0.05).Conclusions In the elderly patients with a small amount of basal ganglia cerebral hemorrhage,there is no indication for operation in the patients with mild hypoperfusion.For patients with severe hypoperfusion,surgery can improve the prognosis.The rCBF in the internal capsule area can be used as a standard for evaluation of the surgical indications of small amount hypertensive basal ganglia hemorrhage in the elderly.关键词
老年/内囊/计算机断层扫描灌注/局部脑血流量/手术指征/高血压性基底核出血Key words
old age/internal capsule/computer tomography perfusion/regional cerebral blood flow/surgical indication/hypertensive basal ganglia hemorrhage分类
医药卫生引用本文复制引用
张卫民,高海晓,张兰,库洪彬,薛振生..应用内囊局部脑血流量规范化评估老年少量基底核出血手术指征的临床研究[J].临床神经外科杂志,2023,20(6):696-700,5.基金项目
邢台市重点研发计划自筹项目(2022ZC105) （2022ZC105）
