临床神经外科杂志2023，Vol.20Issue(6)：709-712,716,5.DOI:10.3969/j.issn.1672-7770.2023.06.021
重型颅脑损伤伴糖尿病酮症酸中毒2例报告并文献复习
Severe traumatic brain injury with diabetic ketoacidosis:a report of 2 cases and literature review
摘要
Abstract
Objective lo investigate the clinical characteristics,blood glucose management,surgical strategy and prognosis of severe traumatic brain injury(sTBI)with diabetic ketoacidosis(DKA).Method The clinical data of 2 patients with sTBI combined with DKA admitted to Department of neurosurgery,The Fifth Affiliated Hospital of Zhengzhou University from August to October 2021 was analyzed retrospectively.The clinical features,radiological images,operation and related literatures were analyzed and discussed,and the prognosis of patients was followed up.Results After these patients were corrected for ketoacidosis,and the traumatic intracranial hematoma was removed under general anesthesia.The blood glucose was adjusted by continuous intravenous pumping of insulin after operation,and the metformin sustained-release tablets were given when the blood glucose was stable during hospitalization.These patients had a good prognosis and had no significant neurological dysfunction after 3 months follow-up.Conclusions Correction of perioperative DKA plays a critical role in the prognosis of patients with TBI.Having a good blood glucose management after operation is an important factor to accelerate the rehabilitation of patients.关键词
重型颅脑损伤/糖尿病酮症酸中毒/昏迷/外科手术/预后Key words
severe traumatic brain injury/diabetic ketoacidosis/coma/surgical operation/prognosis分类
医药卫生引用本文复制引用
蒋战胜,谢井伟,王振,武跃辉,李培栋,单峤,王新军,李信晓..重型颅脑损伤伴糖尿病酮症酸中毒2例报告并文献复习[J].临床神经外科杂志,2023,20(6):709-712,716,5.基金项目
中国抗癫痫协会"CAAE癫痫科研基金"资助项目(CU-2022-002) （CU-2022-002）
河南省科技发展计划项目(182102310158) （182102310158）
