岭南现代临床外科2023，Vol.23Issue(5)：436-443,8.DOI:10.3969/j.issn.1009-976X.2023.05.013
糖基化在慢性炎症性疾病中的作用研究进展
Research progress of glycosylation in chronic inflammatory diseases
摘要
Abstract
Glycosylation is the process by which monosaccharides or glycans are attached to proteins or lipids under the control of glycosyltransferases and glycosidases.Glycosylation is crucial for pathogen infection,intercellular signaling,cell migration,proliferation,and differentiation.Extensive research has demonstrated the significant role of glycosylation in chronic inflammatory diseases,such as inflammatory bowel disease,chronic kidney disease,autoimmune diseases,and cancer.This article provides an over-view of glycosylation and its structural diversity,focusing on the role of glycosylation in the inflammatory microenvironment and its potential feasibility as a diagnostic and therapeutic target for chronic inflamma-tory diseases.It provides theoretical basis and new ideas for the prevention,diagnosis,and treatment of chronic inflammatory diseases based on glycosylation.关键词
糖基化/慢性炎症性疾病/炎症微环境Key words
glycosylation/chronic inflammatory diseases/inflammatory microenvironment分类
医药卫生引用本文复制引用
熊敏敏,苏鸿君,李伟凡,黄松音..糖基化在慢性炎症性疾病中的作用研究进展[J].岭南现代临床外科,2023,23(5):436-443,8.基金项目
国家自然科学基金(82071860) （82071860）
中国博士后科学基金(2022M713618) （2022M713618）
逸仙科研启航项目(YXQH202307) （YXQH202307）
