日用化学工业（中英文）2023，Vol.53Issue(12)：1405-1411,7.DOI:10.3969/j.issn.2097-2806.2023.12.007
生育酚纳米乳液的制备及性能研究
Preparation and properties of α-tocopherol nanoemulsions
摘要
Abstract
To improve the stability and activity of α-tocopherol(α-Toc),a nanoemulsion was prepared by supramolecular inclusion method,which was a kind of nanocarrier for α-Toc with good stability,good transdermal effect and excellent anti-oxidation.The effects of the types of polysorbates(Tweens),the amount of hydroxypropyl β-cyclodextrin(HP-β-CD)and the amount of α-Toc solution on the particle size of the nanoemulsion were investigated.The encapsulation condition and performance evaluation of α-Toc nanoemulsion were studied by Fourier infrared spectroscopy,transmission electron microscopy,nanoparticle size analysis,thermogravimetric analysis and Franz diffusion cell method.The results showed that the obtained α-Toc supramolecular nanoemulsion had small particle size and uniform distribution and had good storage stability both at 0℃and room temperature.This nanoemulsion could significantly enhance the thermal stability of α-Toc,and it showed better antioxidant capacity than the nonencapsulated α-Toc.The nanoemulsion could also effectively promote the transdermal absorption of α-Toc in cosmetic formula.This work could provide research basis for the application of nanocarriers in the field of daily-use chemical industry.关键词
α-生育酚/纳米乳液/超分子/性能研究Key words
α-tocopherol/nano-emulsion/supramolecule/performance study分类
化学化工引用本文复制引用
蔡国强,徐雯雯,权琰,潘卫,张蕾,何一波..生育酚纳米乳液的制备及性能研究[J].日用化学工业（中英文）,2023,53(12):1405-1411,7.基金项目
浙江省"领雁"研发攻关计划项目(2022C01174) （2022C01174）
