山东中医杂志2023，Vol.42Issue(12)：1250-1255,6.DOI:10.16295/j.cnki.0257-358x.2023.12.002
从免疫紊乱角度探讨脓毒症与"阴阳交"的相关性
Correlation between Sepsis and"Interaction of Yin and Yang"from the Perspective of Immune Disorder
摘要
Abstract
Sepsis is a critical emergency in clinic characterized by high morbidity and mortality rate.The major pathogenesis is immune disorder.In recent years,traditional Chinese medicine(TCM)applied for immunomodulation in sepsis has become a emerging hotspot.Based on the modern micro-mechanism of immune disorders,in this paper the correlation between sepsis and interaction of yin and yang in TCM were explored from three aspects:pathogenesis,clinical manifestations and transmission in viscera.Sepsis can be classified into the category of interaction of the yin and yang in TCM.Two major treatment principles,"purging heat"and"supplementing yin",were proposed.Based on comprehensive assessment of disease transmission,deficiency and excess of healthy qi,and accumulation of pathological products,clearing heat and detoxification,tonifying qi and nourishing yin are the major principle,assisted with treating other pathological factors such as phlegm and stasis.Throughout the treatment process,it is essential to protect stomach qi and the bitter and cold medicinals should be applied cautiously.关键词
脓毒症/"阴阳交"/免疫紊乱/微观机制/正邪交争Key words
sepsis/interaction of yin and yang/immune disorder/micro-mechanism/struggle between healthy qi and evil qi分类
医药卫生引用本文复制引用
靳敏燕,胡渊龙,许一飞,侯超,刘影,阮梽坤,陈宪海,邱占军..从免疫紊乱角度探讨脓毒症与"阴阳交"的相关性[J].山东中医杂志,2023,42(12):1250-1255,6.基金项目
国家自然科学基金项目(编号:82274320) （编号:82274320）
山东省自然科学基金项目(编号:ZR2020MH392) （编号:ZR2020MH392）
