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口腔微生物与食管癌关系的研究进展

孙凡钥 杨玉鑫 陈宏伟 师鑫鹏 罗晓勇 王保永

食管疾病2023,Vol.5Issue(4):292-300,310,10.
食管疾病2023,Vol.5Issue(4):292-300,310,10.DOI:10.15926/j.cnki.issn2096-7381.2023.04.010

口腔微生物与食管癌关系的研究进展

Progress of Research on the Relationship between Oral Microorganisms and Esophageal Cancer

孙凡钥 1杨玉鑫 1陈宏伟 1师鑫鹏 1罗晓勇 1王保永1

作者信息

  • 1. 郑州大学洛阳附属中心医院,河南洛阳,471000
  • 折叠

摘要

Abstract

Esophageal cancer is a common malignant tumor of the digestive system,and its etiology is complex and multifaceted.In addition to known factors such as genetic alterations,alcohol consumption,and smoking,several studies have suggested that oral microbiota may play a significant role in the occurrence and development of esophageal cancer.Due to the anatomical continuity between the oral cavity and the esophagus,these two sites have similarities in microbial composition.Therefore,alterations in oral microbiota may impact the microbial ecology of the esophagus,thereby influencing the development of esophageal cancer.This review aims to summarize the research progress on the relationship between oral microbiota and esopha-geal cancer and to compare the differences in their roles in esophageal squamous cell carcinoma and esopha-geal adenocarcinoma,with the goal of providing a theoretical basis for the early prediction and treatment of e-sophageal cancer.

关键词

口腔微生物/食管癌/食管鳞状细胞癌/食管腺癌

Key words

oral microorganisms/esophageal cancer/esophageal squamous cell carcinoma/esophageal adenocarcinoma

分类

医药卫生

引用本文复制引用

孙凡钥,杨玉鑫,陈宏伟,师鑫鹏,罗晓勇,王保永..口腔微生物与食管癌关系的研究进展[J].食管疾病,2023,5(4):292-300,310,10.

基金项目

河南省科技攻关项目(232102311130) (232102311130)

食管疾病

2096-7381

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